Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 9/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL692056 | 0.88 | TSHR (0.40) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL27988075 | 0.85 | TSHR (0.46) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL3278408 | 0.83 | THRB (0.42) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL9817921 | 0.81 | THRB (0.41) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL2046536 | 0.81 | THRB (0.41) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL7623084 | 0.80 | TSHR (0.48) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL302801 | 0.80 | THRB (0.43) | THRBTSHRHPGDALDH1A1TP53 | |
| Chloromethane SCHEMBL8427833 | 0.79 | THRB (0.40) | THRBTSHRHPGDALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL7804778 | 0.79 | THRB (0.40) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL8346412 | 0.78 | THRB (0.39) | THRBTSHRHPGDALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6074761-A | COATING COMPRISES A BINDER CONSISTS OF ORGANIC POLYMER FREE OR AMMONIUM GROUPS, A CATIONIC ADDITION POLYMER CONTAINING QUATERNARY AMMONIUM GROUP, A SECOND ADDITION CATION POLYMER CONTAINING SECONDARY OR TERTIARY AMINE GROUPS, AND A FILLER | PPG INDUSTRIES OHIO, INC. (US) | 2000-06-13 | — | — | US | disclosed |