SCHEMBL692056

SCHEMBL692056

C=CC(=O)OC(N)(CC)CCC

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.40
HPGD P15428 1/20 0.40
THRB P10828 3/20 0.38
ALDH1A1 P00352 5/20 0.32
TP53 P04637 3/20 0.32
HIF1A Q16665 3/20 0.32
CYP3A4 P08684 2/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 2/20 0.32
LMNA P02545 1/20 0.32
FDPS P14324 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27988075 0.89 TSHR (0.46) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL8213754 0.88 THRB (0.42) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL11851858 0.86 TSHR (0.46) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL9193001 0.85 TSHR (0.42) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL1108010 0.82 TSHR (0.44) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL7623084 0.81 TSHR (0.48) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL16291333 0.77 TSHR (0.42) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL3247427 0.77 TSHR (0.42) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL5271167 0.76 TSHR (0.45) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL16291088 0.76 TSHR (0.45) TSHRHPGDTHRBALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4454304-A CONJUGATED DIENE RUBBER BLENDS COPOLYMER RUBBER & CHEMICAL CORP. (US) 1984-06-12 US claimed
CN-115551958-A Inkjet inks for printed circuit boards 爱克发-格法特公司 2022-12-30 CN disclosed
CN-115485343-A Inkjet inks for printed circuit boards 爱克发-格法特公司 2022-12-16 CN disclosed
EP-2421926-B1 OPTICAL FIBER WITH SINGLE COATING PRYSMIAN SPA (IT) 2017-08-16 EP disclosed
US-8792761-B2 Optical fiber with single coating PRYSMIAN S.P.A. (IT) 2014-07-29 US disclosed
US-20120093470-A1 OPTICAL FIBER WITH SINGLE COATING PRYSMIAN S.P.A. (IT) 2012-04-19 US disclosed
EP-2421926-A1 OPTICAL FIBER WITH SINGLE COATING Prysmian S.p.A. (IT) 2012-02-29 EP disclosed
US-8067633-B2 Method for the synthesis of (meth)acrylic esters catalysed by a polyol titanate ARKEMA FRANCE (FR) 2011-11-29 US disclosed
WO-2010121659-A1 OPTICAL FIBER WITH SINGLE COATING PRYSMIAN S.P.A. (IT) 2010-10-28 WO disclosed
US-7820265-B2 Electrically heatable pressure-sensitive adhesive compound TESA SE (DE) 2010-10-26 US disclosed
US-20060041044-A1 Method for the production of acrylate adhesive materials using metal-sulphur compounds TESA SE (DE) 2006-02-23 US disclosed
EP-1286225-B1 Developing assembly, process cartridge and image-forming method CANON KK (JP) 2005-11-09 EP disclosed
US-20050187346-A1 Pressure-sensitive adhesive based on acrylate block copolymers TESA AKTIENGESELLSCHAFT (DE) 2005-08-25 US disclosed
US-6924076-B2 Developing assembly, process cartridge and image-forming method CANON KABUSHIKI KAISHA (JP) 2005-08-02 US disclosed
US-20030215731-A1 Developing assembly, process cartridge and image-forming method CANON KABUSHIKI KAISHA (JP) 2003-11-20 US disclosed
EP-1286225-A2 Developing assembly, process cartridge and image-forming method CANON KABUSHIKI KAISHA (JP) 2003-02-26 EP disclosed
US-5958392-A HAIR CONNDITIONERS COMPRISING A BLEND OF AMPHOTERIC ADDITION POLYMERS CONTAINING AMINE AND CARBOXY OR SULFO GROUPS AND A QUAATERNIZED VINYLPYRROLIDONE/AMINOALCOHOL ACRYLATE COPOLYMER; SOFTNESS; SILKY FEEL L'OREAL (FR) 1999-09-28 US disclosed
US-5773545-A Polymers of alkyl-1-vinylimidazloes, the preparation and use thereof BASF AKTIENGESELLSCHAFT (DE) 1998-06-30 US disclosed
US-5684109-A WATER TREATMENT BETZDEARBORN INC. (US) 1997-11-04 US disclosed
US-4639395-A LAYER OF ANIONIC POLYMER; LAYER OF ALKALINE MATERIAL AND CATIONIC POLYMER ALLIED COLLOIDS LIMITED (GB) 1987-01-27 US disclosed