Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29089114 | 0.74 | PLA2G2A (0.53) | PLA2G10PLA2G2AALDH1A1MAPTHPGD | |
| SCHEMBL15621741 | 0.71 | PLA2G2A (0.50) | PLA2G10PLA2G2AALDH1A1MAPTHPGD | |
| SCHEMBL28681774 | 0.70 | PLA2G2A (0.57) | PLA2G10PLA2G2AALDH1A1MAPTHPGD | |
| SCHEMBL28869488 | 0.69 | PLA2G10 (0.41) | PLA2G10PLA2G2AALDH1A1MAPTHPGD | |
| SCHEMBL45809 | 0.69 | HTT (0.45) | PLA2G10PLA2G2AHSD17B10LIMK1HTT | |
| SCHEMBL11901445 | 0.68 | PLA2G2A (0.46) | PLA2G10PLA2G2AALDH1A1MAPTHPGD | |
| Diphenylmethane SCHEMBL18604552 | 0.68 | PLA2G10 (0.71) | PLA2G10PLA2G2AMAPTRECQLHSD17B10 | |
| Diphenylmethane SCHEMBL8743340 | 0.68 | PLA2G10 (0.71) | PLA2G10PLA2G2AMAPTRECQLHSD17B10 | |
| Diphenylmethane SCHEMBL28144267 | 0.68 | PLA2G10 (0.71) | PLA2G10PLA2G2AMAPTRECQLHSD17B10 | |
| Diphenylmethane SCHEMBL10451543 | 0.68 | PLA2G10 (0.71) | PLA2G10PLA2G2AMAPTRECQLHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6137011-A | CATALYTICALLY HYDROGENATINING BISTRIFLUOROMETHYLBENZONITRILE, IN PRESENCE OF RANEY COBALT,ALIPHATIC ETHER, AND AMMONIA TO FORM BISTRIFLUOROMETHYLBENZYL-AMINE | BAYER AKTIENGESELLSCHAFT (DE) | 2000-10-24 | — | — | US | disclosed |