Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17583816 | 0.71 | CYP19A1 (0.54) | CYP11B1CYP11B2CYP19A1KDM4EHSD17B10 | |
| SCHEMBL25968371 | 0.71 | EGLN2 (0.42) | CYP1A2CYP3A4CYP2D6CYP2C19PDE3B | |
| SCHEMBL13925882 | 0.70 | CYP1A2 (0.39) | CCNE1CDK2CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL31589030 | 0.69 | CYP19A1 (0.55) | CYP11B1CYP11B2CYP19A1KDM4EHSD17B10 | |
| SCHEMBL31589323 | 0.68 | CYP11B1 (0.54) | CYP11B1CYP11B2CYP19A1KDM4EHSD17B10 | |
| SCHEMBL18263064 | 0.67 | CYP11B1 (0.49) | CYP11B1CYP11B2CYP19A1KDM4EHSD17B10 | |
| SCHEMBL13906524 | 0.67 | ALDH1A1 (0.49) | KDM4EHSD17B10HPGDTDP1LMNA | |
| SCHEMBL10654946 | 0.67 | KDM4E (0.57) | KDM4EHSD17B10HPGDALDH1A1MAPK1 | |
| SCHEMBL5844344 | 0.65 | POLB (0.48) | KDM4EHSD17B10HPGDLMNAALDH1A1 | |
| SCHEMBL13914376 | 0.65 | ALDH1A1 (0.47) | KDM4EHSD17B10HPGDALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008019266-A2 | ACYCLIC, PYRIDAZINONE-DERIVED HEPATITIS C SERINE PROTEASE INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2008-02-14 | — | — | WO | disclosed |