SCHEMBL821425

SCHEMBL821425

Cc1ccc[c]c1C1(C)CCCCC1

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 1/20 0.33
PDE7A Q13946 1/20 0.31
HDAC4 P56524 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL821424 0.74 GLA (0.33) PDE7AHDAC4
SCHEMBL25673 0.69 SLC6A4 (0.31)
SCHEMBL6152617 0.68 HDAC4 (0.49) P2RX7PDE7AHDAC4
Benzene SCHEMBL28837788 0.67 HDAC4 (0.47) P2RX7PDE7AHDAC4
SCHEMBL11800826 0.66 HDAC4 (0.50) P2RX7PDE7AHDAC4
SCHEMBL16033418 0.65 PDE7A (0.42) P2RX7PDE7AHDAC4
SCHEMBL11201749 0.63 GLA (0.33)
SCHEMBL27969360 0.63 ESR1 (0.33)
SCHEMBL16720223 0.63 ESR1 (0.31)
Toluene SCHEMBL28118544 0.63 HDAC4 (0.44) P2RX7PDE7AHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2386582-B1 Preparation of a solid catalyst system BOREALIS AG (AT) 2016-02-17 EP disclosed
US-8962509-B2 Preparation of a solid catalyst system BOREALIS AG (AT) 2015-02-24 US disclosed
EP-2738183-A1 Preparation of a solid catalyst system Borealis AG (AT) 2014-06-04 EP disclosed
EP-2386581-B1 Preparation of a solid catalyst system BOREALIS AG (AT) 2014-03-26 EP disclosed
US-20130253152-A1 PREPARATION OF A SOLID CATALYST SYSTEM BOREALIS AG (AT) 2013-09-26 US disclosed
EP-2386581-A1 Preparation of a solid catalyst system Borealis AG (AT) 2011-11-16 EP disclosed
EP-2386582-A1 Preparation of a solid catalyst system Borealis AG (AT) 2011-11-16 EP disclosed
WO-2011138214-A1 PREPARATION OF A SOLID CATALYST SYSTEM BOREALIS AG (AT) 2011-11-10 WO disclosed
WO-2011138212-A1 PREPARATION OF A SOLID CATALYST SYSTEM BOREALIS AG (AT) 2011-11-10 WO disclosed
US-20110252631-A1 Method of manufacturing a thin-film magnetic head TDK CORPORATION (JP) 2011-10-20 US disclosed
US-20110252562-A1 ADJUSTABLE-FIRMNESS BODY SUPPORT AND METHOD SEALY TECHNOLOGY LLC 2011-10-20 US disclosed