Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25673 | 0.73 | SLC6A4 (0.31) | — | |
| SCHEMBL6390940 | 0.72 | GLA (0.36) | GLATSHRALOX12ATM | |
| SCHEMBL27969360 | 0.70 | ESR1 (0.33) | — | |
| SCHEMBL2826512 | 0.69 | — | — | |
| SCHEMBL16029802 | 0.65 | HDAC4 (0.50) | — | |
| SCHEMBL1246246 | 0.64 | TSHR (0.39) | TSHR | |
| SCHEMBL224914 | 0.64 | ALOX12 (0.50) | GLATSHRALOX12ATM | |
| SCHEMBL4987796 | 0.63 | KMT2A (0.41) | — | |
| SCHEMBL821425 | 0.63 | P2RX7 (0.33) | — | |
| SCHEMBL821424 | 0.63 | GLA (0.33) | GLATSHRALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4378443-A | 2,2,6,6-Tetraalkyl-4-piperidyl-bix-spiro-ethers as light stabilizers for synthetic polymers | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1983-03-29 | — | — | US | disclosed |