SCHEMBL821426

SCHEMBL821426

[C-]#[N+]c1ccc(C(=O)Nc2cc(OC)nc(NC(=O)c3ccc(C#N)cc3)n2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 5/20 0.47
▸ RAB9A P51151 5/20 0.47
▸ SMN1; SMN2 Q16637 3/20 0.47
▸ TP53 P04637 1/20 0.47
▸ NFKB1 P19838 1/20 0.47
▸ NFKB2 Q00653 1/20 0.47
▸ RELA Q04206 1/20 0.47
▸ DEGS1 O15121 1/20 0.42
▸ DUSP3 P51452 1/20 0.41
▸ ADORA2A P29274 2/20 0.41
▸ ADORA1 P30542 2/20 0.41
▸ KMT2A Q03164 3/20 0.40
▸ MAPT P10636 3/20 0.40
▸ KDM4E B2RXH2 2/20 0.40
▸ MEN1 O00255 2/20 0.40
▸ RECQL P46063 1/20 0.40
▸ ALDH1A1 P00352 4/20 0.40
▸ PKM P14618 1/20 0.40
▸ ADORA2B P29275 1/20 0.40
▸ CASP3 P42574 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10084355 0.91 NPC1 (0.55) NPC1RAB9ASMN1; SMN2TP53NFKB1
SCHEMBL15308197 0.77 NPC1 (0.60) NPC1RAB9ASMN1; SMN2TP53NFKB1
SCHEMBL823170 0.77 NPC1 (0.76) NPC1RAB9ASMN1; SMN2TP53NFKB1
SCHEMBL15308198 0.77 NPC1 (0.60) NPC1RAB9ASMN1; SMN2TP53NFKB1
SCHEMBL821789 0.77 RAB9A (0.60) NPC1RAB9ASMN1; SMN2TP53NFKB1
SCHEMBL15305681 0.77 RAB9A (0.60) NPC1RAB9ASMN1; SMN2TP53NFKB1
SCHEMBL15308166 0.76 NPC1 (0.59) NPC1RAB9ASMN1; SMN2TP53NFKB1
SCHEMBL821769 0.76 KMT2A (0.64) NPC1RAB9ASMN1; SMN2TP53NFKB1
SCHEMBL821800 0.75 SMN1; SMN2 (0.57) NPC1RAB9ASMN1; SMN2TP53NFKB1
SCHEMBL822100 0.74 NPC1 (0.56) NPC1RAB9ASMN1; SMN2TP53NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9151883-B2 Cellulose acylate film, retardation film, polarizer and liquid-crystal display device FUJIFILM CORPORATION (JP) 2015-10-06 — — US disclosed
US-8937696-B2 Cellulose acylate film, its production method, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2015-01-20 — — US disclosed
US-8906475-B2 Cellulose acylate film, retardation film, polarizer and liquid-crystal display device FUJIFILM CORPORATION (JP) 2014-12-09 — — US disclosed
US-20140318413-A1 CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2014-10-30 — — US disclosed
US-8792071-B2 Cellulose acylate film, its production method, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2014-07-29 — — US disclosed
US-20140053755-A1 Cellulose Acylate Film, Retardation Film, Polarizer and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2014-02-27 — — US disclosed
US-20120268693-A1 CELLULOSE ACYLATE FILM, POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-10-25 — — US disclosed
US-20120268694-A1 CELLULOSE ACYLATE FILM, METHOD FOR PRODUCING SAME, POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-10-25 — — US disclosed
US-20120249933-A1 CELLULOSE ACYLATE FILM, ITS PRODUCTION METHOD, POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-10-04 — — US disclosed
US-20120231217-A1 OPTICAL FILM, PHASE DIFFERENCE FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-09-13 — — US disclosed
US-20120204757-A1 Cellulose Acylate Film, Retardation Film, Polarizer and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2012-08-16 — — US disclosed
US-20120180697-A1 CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-07-19 — — US disclosed
US-20120177848-A1 CELLULOSE ACYLATE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-07-12 — — US disclosed
US-8158220-B2 Cellulose acylate film, retardation film, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-04-17 — — US disclosed
US-20120018685-A1 Optical film, retardation film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-01-26 — — US disclosed
US-20110255037-A1 Cellulose acylate film, its production method, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2011-10-20 — — US disclosed
US-20110076423-A1 CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2011-03-31 — — US disclosed
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