Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8215469 | 0.89 | GSK3B (0.41) | GSK3BCA1CA2SLC6A3ALDH1A1 | |
| SCHEMBL10765330 | 0.82 | AKR1C1 (0.44) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL10765334 | 0.82 | AKR1C1 (0.44) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL8214853 | 0.81 | CA1 (0.44) | GSK3BCA1CA2ALDH1A1MAPT | |
| SCHEMBL8214861 | 0.80 | SMN1; SMN2 (0.47) | GSK3BALDH1A1MAPTRAB9AKMT2A | |
| SCHEMBL8219253 | 0.77 | CA1 (0.41) | GSK3BCA1CA2ALDH1A1MAPT | |
| SCHEMBL20597715 | 0.75 | EP300 (0.45) | GSK3BCA1CA2SLC6A3ALDH1A1 | |
| SCHEMBL8214414 | 0.75 | KMT2A (0.37) | PARP10KMT2AMEN1 | |
| SCHEMBL27746186 | 0.74 | CA2 (0.47) | GSK3BCA1CA2ALDH1A1MAPT | |
| SCHEMBL31580973 | 0.74 | CYP1A2 (0.47) | ALDH1A1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6106908-A | OPTICAL APPARATUS WITH LIQUID CRYSTAL COMPOUNDS | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 2000-08-22 | — | — | US | disclosed |