Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | P4HB | P07237 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8219253 | 0.95 | CA1 (0.41) | CA1CA2PARP15PARP10PARP2 | |
| SCHEMBL8216150 | 0.83 | XDH (0.39) | PARP2 | |
| SCHEMBL8215469 | 0.83 | GSK3B (0.41) | CA1CA2PARP15PARP10PARP2 | |
| SCHEMBL8219853 | 0.83 | LDHA (0.40) | ALDH1A1L3MBTL1KDM4ERAB9ANPC1 | |
| SCHEMBL8217219 | 0.83 | KDM4E (0.42) | PARP2ALDH1A1L3MBTL1KDM4ERAB9A | |
| SCHEMBL8214690 | 0.81 | GSK3B (0.40) | CA1CA2PARP15PARP10PARP2 | |
| SCHEMBL27746186 | 0.80 | CA2 (0.47) | CA1CA2PARP15PARP10PARP2 | |
| SCHEMBL23934153 | 0.80 | CA2 (0.41) | CA1CA2PARP15PARP10PARP2 | |
| SCHEMBL4364435 | 0.79 | AKR1C1 (0.52) | CA1CA2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL8343039 | 0.79 | AKR1C1 (0.52) | CA1CA2ALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6106908-A | OPTICAL APPARATUS WITH LIQUID CRYSTAL COMPOUNDS | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 2000-08-22 | — | — | US | disclosed |