SCHEMBL8214940

SCHEMBL8214940

CCCCCCOc1cccc(-c2c(F)cccc2-c2cccc(C#N)c2)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.43
CNR2 P34972 1/20 0.43
CYP11B1 P15538 1/20 0.43
CYP11B2 P19099 1/20 0.43
TSHR P16473 1/20 0.42
KDM4E B2RXH2 2/20 0.41
ALDH1A1 P00352 2/20 0.41
HPGD P15428 2/20 0.41
HTT P42858 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
PTPN11 Q06124 1/20 0.40
PLA2G4B P0C869 2/20 0.40
GABRG2 P18507 2/20 0.40
GABRB3 P28472 2/20 0.40
GABRA5 P31644 2/20 0.40
GABRA3 P34903 2/20 0.40
SMPD1 P17405 3/20 0.40
CYP1A2 P05177 1/20 0.40
CYP19A1 P11511 1/20 0.40
CYP2C9 P11712 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8209308 1.00 CNR1 (0.43) CNR1CNR2CYP11B1CYP11B2TSHR
SCHEMBL8208402 1.00 CNR1 (0.43) CNR1CNR2CYP11B1CYP11B2TSHR
SCHEMBL8214987 1.00 CNR1 (0.43) CNR1CNR2CYP11B1CYP11B2TSHR
SCHEMBL8215684 1.00 CNR1 (0.43) CNR1CNR2CYP11B1CYP11B2TSHR
SCHEMBL8217689 0.99 CYP11B1 (0.44) CNR1CNR2CYP11B1CYP11B2TSHR
SCHEMBL8215774 0.96 CYP11B1 (0.47) CNR1CNR2CYP11B1CYP11B2KDM4E
SCHEMBL8208505 0.92 GABRG2 (0.42) CYP11B1CYP11B2KDM4EALDH1A1GABRG2
SCHEMBL8218491 0.88 GABRG2 (0.47) CNR2CYP11B1CYP11B2KDM4EALDH1A1
SCHEMBL9682289 0.87 CNR1 (0.49) CNR1CNR2CYP11B1CYP11B2TSHR
SCHEMBL8218520 0.81 SQOR (0.44) TSHRKDM4EALDH1A1L3MBTL1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1022324-A2 Liquid crystal composite material and liquid crystal display device(s) which use them SEIKO EPSON CORPORATION (JP) 2000-07-26 EP disclosed
US-5972240-A LIQUID CRYSTAL COMPOSITE MATERIALS CONTAINING ORGANIC COMPOUNDS ENABLE THE LOWERING OF THE DRIVE VOLTAGE OF LIQUID CRYSTAL DISPLAY DEVICES AND OF LIQUID CRYSTAL DISPLAY DEVICES OF A POLYMER-DISPERSION TYPE SEIKO EPSON CORPORATION (JP) 1999-10-26 US disclosed
EP-0730019-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT PRODUCED THEREFROM SEIKO EPSON CORPORATION (JP) 1996-09-04 EP disclosed