Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 3/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.30 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8201898 | 1.00 | CTSC (0.34) | CTSCEPHX2SSTR4CYP2C19HIF1A | |
| SCHEMBL16555962 | 0.83 | GRIK1 (0.41) | CTSCCYP2C19GRIK1GRIA2 | |
| SCHEMBL7143064 | 0.83 | GRIK1 (0.41) | CTSCCYP2C19GRIK1GRIA2 | |
| SCHEMBL7137595 | 0.78 | CTSC (0.33) | CTSCEPHX2KIF11CHRM3 | |
| SCHEMBL7137589 | 0.76 | CTSC (0.41) | CTSCSSTR4KIF11 | |
| SCHEMBL7143845 | 0.74 | POLB (0.39) | CTSCKMT2A | |
| SCHEMBL7137646 | 0.70 | TLR2 (0.31) | — | |
| SCHEMBL5405202 | 0.70 | TLR2 (0.31) | — | |
| SCHEMBL5401320 | 0.69 | KIF11 (0.34) | KIF11KMT2A | |
| SCHEMBL5401316 | 0.69 | KIF11 (0.34) | KIF11KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054865-A1 | FARNESYL TRANSFERASE INHIBITORS | AstraZeneca UK Limited (GB) | 2000-11-29 | — | — | EP | disclosed |
| WO-1999041235-A1 | FARNESYL TRANSFERASE INHIBITORS | ASTRAZENECA UK LIMITED (GB) | 1999-08-19 | — | — | WO | disclosed |