Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.46 |
| ▸ | FAP | Q12884 | 2/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.46 |
| ▸ | PREP | P48147 | 2/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8212218 | 0.87 | F2 (0.49) | ACE | |
| SCHEMBL8210445 | 0.85 | DPP4 (0.47) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL4727350 | 0.85 | DPP4 (0.47) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL4725996 | 0.84 | DPP4 (0.64) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL4725994 | 0.84 | DPP4 (0.64) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL4727239 | 0.81 | ITGB3 (0.54) | ACE | |
| SCHEMBL4081470 | 0.81 | ITGB3 (0.54) | ACE | |
| SCHEMBL8215243 | 0.81 | DPP4 (0.53) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL8213080 | 0.80 | KLK5 (0.48) | — | |
| SCHEMBL4086307 | 0.80 | KLK5 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008029217-A2 | DIPEPTIDYL PEPTIDASE IV INHIBITORS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2008-03-13 | — | — | WO | disclosed |