Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8213080 | 1.00 | KLK5 (0.48) | KLK5HDAC8 | |
| SCHEMBL4081470 | 0.91 | ITGB3 (0.54) | HDAC8 | |
| SCHEMBL4727239 | 0.91 | ITGB3 (0.54) | HDAC8 | |
| SCHEMBL8203641 | 0.89 | HDAC8 (0.46) | HDAC8 | |
| SCHEMBL7105102 | 0.84 | KLK5 (0.52) | KLK5HDAC8 | |
| SCHEMBL2294118 | 0.84 | KLK5 (0.61) | KLK5HDAC8 | |
| SCHEMBL29721250 | 0.84 | KLK5 (0.61) | KLK5HDAC8 | |
| SCHEMBL2294112 | 0.84 | KLK5 (0.61) | KLK5HDAC8 | |
| SCHEMBL29103443 | 0.84 | KLK5 (0.61) | KLK5HDAC8 | |
| SCHEMBL1151387 | 0.82 | KLK5 (0.51) | KLK5HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090082408-A1 | NOVEL HETEROCYCLIC DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2009-03-26 | — | — | US | disclosed |
| US-20090082408-A1 | NOVEL HETEROCYCLIC DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2009-03-26 | — | — | US | disclosed |
| US-20090082408-A1 | NOVEL HETEROCYCLIC DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2009-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090082408-A1 | NOVEL HETEROCYCLIC DERIVATIVES | CYP3A5, CYP3A7, UGT2B7 | KLK5 1276/4885HDAC8 1113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.