Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TOP1 | P11387 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | AGXT | P21549 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8343041 | 0.89 | MAOB (0.54) | LMNAALDH1A1GPR52MAOBTOP1 | |
| SCHEMBL10596492 | 0.89 | MAOB (0.54) | LMNAALDH1A1GPR52MAOBTOP1 | |
| SCHEMBL7364003 | 0.87 | LMNA (0.52) | LMNAABCC4GAATSHRPTGS1 | |
| SCHEMBL8219242 | 0.87 | BCL2L1 (0.42) | LMNAGAAALDH1A1MAOBSMN1; SMN2 | |
| SCHEMBL8207836 | 0.84 | MCL1 (0.46) | ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL8219773 | 0.83 | GPR52 (0.59) | LMNAABCC4GAATSHRPTGS1 | |
| SCHEMBL8219248 | 0.83 | HDAC2 (0.46) | TSHRHTTMMP12MMP13IDO1 | |
| SCHEMBL8214644 | 0.82 | ANPEP (0.37) | — | |
| SCHEMBL8219175 | 0.82 | CYP17A1 (0.41) | LMNAKDM4E | |
| SCHEMBL11219683 | 0.81 | LPAR2 (0.42) | LMNAABCC4GAATSHRPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6106908-A | OPTICAL APPARATUS WITH LIQUID CRYSTAL COMPOUNDS | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 2000-08-22 | — | — | US | disclosed |