Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL166975 | 0.88 | — | — | |
| Acetic Acid SCHEMBL27700581 | 0.82 | ALDH1A1 (0.50) | ALDH1A1SOAT1LMNAHSD17B10MEN1 | |
| SCHEMBL28098998 | 0.81 | ALDH1A1 (0.62) | ALDH1A1SOAT1LMNAHSD17B10CYP2C19 | |
| SCHEMBL14751639 | 0.80 | ALDH1A1 (0.54) | ALDH1A1SOAT1LMNAHSD17B10CYP2C19 | |
| Butadiene SCHEMBL28418545 | 0.80 | ALDH1A1 (0.48) | ALDH1A1SOAT1LMNAHSD17B10CYP2C19 | |
| SCHEMBL13248945 | 0.80 | ALDH1A1 (0.54) | ALDH1A1SOAT1LMNAHSD17B10CYP2C19 | |
| Adamantane SCHEMBL8214531 | 0.78 | CHRNB2 (0.34) | HSD11B1 | |
| Adamantane SCHEMBL6706214 | 0.76 | TSHR (0.48) | ALDH1A1LMNAMAPK1HSD17B10CYP3A4 | |
| SCHEMBL27897704 | 0.74 | ALDH1A1 (0.56) | ALDH1A1SOAT1LMNAHSD17B10CYP2C19 | |
| SCHEMBL9000997 | 0.73 | CA1 (0.37) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166236-A | Vinyl carbonate and vinyl carbamate contact lens material monomers | BAUSCH & LOMB INCORPORATED (US) | 2000-12-26 | — | — | US | claimed |
| EP-0396364-B1 | Copolymers of vinyl carbonate and vinyl carbamate as contact lens material | BAUSCH & LOMB (US) | 1997-06-11 | — | — | EP | claimed |
| US-5610252-A | Vinyl carbonate and vinyl carbamate contact lens material monomers | BAUSCH & LOMB INCORPORATED (US) | 1997-03-11 | — | — | US | claimed |
| EP-0396364-A2 | Novel vinyl carbonate and vinyl carbamate contact lens material monomers | BAUSCH & LOMB INCORPORATED (US) | 1990-11-07 | — | — | EP | claimed |
| EP-0396364-B1 | Copolymers of vinyl carbonate and vinyl carbamate as contact lens material | BAUSCH & LOMB (US) | 1997-06-11 | — | — | EP | disclosed |