SCHEMBL8215438

SCHEMBL8215438

CCCC(=O)CSC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27503888 0.84
SCHEMBL27503491 0.82 KMT2A (0.52)
SCHEMBL10979712 0.80 KMT2A (0.56)
SCHEMBL5959382 0.79 ALDH1A1 (0.36)
SCHEMBL2112269 0.78
SCHEMBL25964823 0.78
SCHEMBL811352 0.77
SCHEMBL26447122 0.76 CES2 (0.41)
SCHEMBL14037204 0.76 EGLN1 (0.48)
SCHEMBL26447205 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2931854-A1 FRAGRANCE MATERIALS The Procter & Gamble Company (US) 2015-10-21 EP claimed
WO-2014093807-A1 FRAGRANCE MATERIALS THE PROCTER & GAMBLE COMPANY (US) 2014-06-19 WO claimed
US-8946144-B2 Phosphonated glycopeptide and lipoglycopeptide antibiotics and uses thereof for the prevention and treatment of bone and joint infections THE MEDICINES COMPANY (US) 2015-02-03 US disclosed
US-8901072-B2 Glycopeptide and lipoglycopeptide antibiotics with improved solubility THE MEDICINES COMPANY (US) 2014-12-02 US disclosed
US-20140194480-A1 METHODS FOR THE CONTROL OF TERMITES AND ANTS SYNGENTA PARTICIPATIONS AG (CH) 2014-07-10 US disclosed
US-20130210623-A1 PESTICIDAL MIXTURES INCLUDING ISOXAZOLINE DERIVATIVES SYNGENTA CROP PROTECTION LLC (US) 2013-08-15 US disclosed
US-20130203591-A1 PESTICIDAL MIXTURES INCLUDING ISOXAZOLINE DERIVATIVES SYNGENTA CROP PROTECTION LLC (US) 2013-08-08 US disclosed
US-20120149632-A1 GLYCOPEPTIDE AND LIPOGLYCOPEPTIDE ANTIBIOTICS WITH IMPROVED SOLUBILITY THE MEDICINES COMPANY (US) 2012-06-14 US disclosed
EP-1054865-A1 FARNESYL TRANSFERASE INHIBITORS AstraZeneca UK Limited (GB) 2000-11-29 EP disclosed
WO-1999041235-A1 FARNESYL TRANSFERASE INHIBITORS ASTRAZENECA UK LIMITED (GB) 1999-08-19 WO disclosed