Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16031738 | 0.72 | KCNH2 (0.31) | — | |
| SCHEMBL7010502 | 0.72 | DRD2 (0.47) | DRD2DRD3HTR1AHTR2A | |
| SCHEMBL188447 | 0.72 | DRD2 (0.54) | DRD2DRD3HTR1A | |
| SCHEMBL30100996 | 0.70 | DRD2 (0.45) | DRD2DRD3HTR1AHTR2A | |
| SCHEMBL1492682 | 0.70 | DRD2 (0.56) | DRD2DRD3HTR1A | |
| SCHEMBL30100957 | 0.70 | HTR1A (0.42) | DRD2DRD3HTR1A | |
| SCHEMBL31284382 | 0.70 | DRD2 (0.45) | DRD2DRD3HTR1A | |
| SCHEMBL4536932 | 0.69 | DRD2 (0.65) | DRD2DRD3HTR1AHTR2A | |
| SCHEMBL1626963 | 0.69 | DRD2 (0.65) | DRD2DRD3HTR1AHTR2A | |
| SCHEMBL357358 | 0.69 | DRD2 (0.65) | DRD2DRD3HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000023444-A1 | 5,7-DISUBSTITUTED-4-AMINOPYRIDO[2,3-D]PYRIMIDINE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-04-27 | — | — | WO | claimed |
| WO-2000023444-A1 | 5,7-DISUBSTITUTED-4-AMINOPYRIDO[2,3-D]PYRIMIDINE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-04-27 | — | — | WO | disclosed |