Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 12/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SPHK2 | Q9NRA0 | 6/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8208472 | 1.00 | RARB (0.38) | RARBSPHK1CYP2C9FFAR4CYP3A4 | |
| SCHEMBL8210666 | 0.96 | SPHK1 (0.42) | RARBSPHK1CYP2C9FFAR4CYP3A4 | |
| SCHEMBL8217731 | 0.94 | RARB (0.40) | RARBSPHK1CYP2C9FFAR4CYP3A4 | |
| SCHEMBL8215881 | 0.94 | RARB (0.40) | RARBSPHK1CYP2C9FFAR4CYP3A4 | |
| SCHEMBL8215738 | 0.93 | CYP2C9 (0.39) | RARBSPHK1CYP2C9FFAR4CYP3A4 | |
| SCHEMBL8218450 | 0.93 | CYP2C9 (0.39) | RARBSPHK1CYP2C9FFAR4CYP3A4 | |
| SCHEMBL8216095 | 0.92 | ALDH1A1 (0.38) | RARBSPHK1CYP2C9FFAR4CYP3A4 | |
| SCHEMBL8220268 | 0.92 | RARB (0.38) | RARBSPHK1CYP2C9FFAR4CYP3A4 | |
| SCHEMBL17759277 | 0.90 | SPHK1 (0.46) | RARBSPHK1CYP2C9CYP3A4ALDH1A1 | |
| SCHEMBL9775767 | 0.88 | SPHK1 (0.48) | RARBSPHK1CYP2C9FFAR4CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117361-A | FOUR RING COMPOUND HAVING AN ALKYL GROUP SUBSTITUTED WITH ONE OR MORE ETHERS, AND A HALOGEN ATOM SUBSTITUTED BENZENE RING; BROAD TEMPERATURE RANGE OF NEMATIC PHASE, HIGHER MISCIBILITY WITH OTHER LIQUID CRYSTAL COMPOUNDS, AND CHEMICAL STABILITY | CHISSO CORP. (JP) | 2000-09-12 | — | — | US | disclosed |
| EP-0891961-A1 | LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED 1,4-PHENYLENE SKELETONS, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES | CHISSO CORPORATION (JP) | 1999-01-20 | — | — | EP | disclosed |