Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | NOS1 | P29475 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3285131 | 0.82 | ELANE (0.38) | NOS1KMT2AELANEPLAULMNA | |
| SCHEMBL8196306 | 0.82 | POLB (0.44) | SMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL22798569 | 0.82 | POLB (0.44) | SMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL17654422 | 0.81 | RAB9A (0.32) | NOS1KMT2AL3MBTL1ELANERAB9A | |
| SCHEMBL13518680 | 0.81 | RAB9A (0.32) | NOS1KMT2AL3MBTL1ELANERAB9A | |
| SCHEMBL13518677 | 0.81 | RAB9A (0.32) | NOS1KMT2AL3MBTL1ELANERAB9A | |
| SCHEMBL8196529 | 0.80 | NOS1 (0.39) | NOS1ALDH1A1ELANERAB9A | |
| SCHEMBL24177802 | 0.79 | PCSK9 (0.33) | NOS1KMT2AALDH1A1NLRP3ELANE | |
| SCHEMBL14936429 | 0.76 | ELANE (0.38) | NOS1ELANEPLAU | |
| SCHEMBL8195539 | 0.76 | ELANE (0.34) | SMN1; SMN2NOS1ELANEPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000078723-A1 | PROCESS FOR THE PREPARATION OF BUTOXYCARBONYLIMINO COMPOUNDS AND INTERMEDIATES THEREFOR | GLAXO GROUP LIMITED (GB) | 2000-12-28 | — | — | WO | disclosed |