SCHEMBL8215992

SCHEMBL8215992

CCOC(OCC)(C(C)C)C(C)C

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1142718 0.83
SCHEMBL9501407 0.75 HSD17B10 (0.35)
SCHEMBL1286179 0.73 LMNA (0.35) LMNATHRB
SCHEMBL9496225 0.71 LMNA (0.33) LMNA
SCHEMBL5699322 0.71
SCHEMBL15611678 0.69 LMNA (0.32) LMNA
SCHEMBL387804 0.69
SCHEMBL12298339 0.69
SCHEMBL8645121 0.69 ALDH1A1 (0.35) LMNA
SCHEMBL6602092 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0580308-B1 Working fluid composition for refrigeration machine KAO CORP (JP) 2000-11-15 EP disclosed
US-5395544-A Ester-containing working fluid composition for refrigerating machine KAO CORPORATION (JP) 1995-03-07 US disclosed
EP-0580308-A1 Working fluid composition for refrigeration machine KAO CORPORATION (JP) 1994-01-26 EP disclosed
EP-0272110-B1 ERYTHROMYCIN A DERIVATIVES AND METHOD FOR THE PREPARATION OF THE SAME TAISHO PHARMACEUTICAL CO. LTD (JP) 1993-04-07 EP disclosed
US-4990602-A Bactericides TAISHO PHARMACEUTICAL CO., LTD. (JP) 1991-02-05 US disclosed
EP-0272110-A2 Erythromycin a derivatives and method for the preparation of the same TAISHO PHARMACEUTICAL CO. LTD (JP) 1988-06-22 EP disclosed