Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC1 | P19801 | 2/20 | 0.52 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KDM6B | O15054 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | IAPP | P10997 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CCNC | P24863 | 4/20 | 0.37 |
| ▸ | CDK8 | P49336 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2999880 | 0.84 | AOC1 (0.53) | AOC1AOC3ALDH1A1KDM4ETDP1 | |
| SCHEMBL8071332 | 0.82 | AOC1 (0.55) | AOC1AOC3ALDH1A1KDM4ETDP1 | |
| SCHEMBL4378971 | 0.82 | CCNC (0.54) | AOC1AOC3ALDH1A1KDM4ETDP1 | |
| SCHEMBL3651691 | 0.80 | CYP4F2 (0.50) | AOC1AOC3ALDH1A1KDM4EMAPT | |
| SCHEMBL2995694 | 0.78 | AOC1 (0.50) | AOC1AOC3ALDH1A1KDM4ETDP1 | |
| SCHEMBL25046268 | 0.77 | SIRT3 (0.44) | ALDH1A1TDP1KDM4CIAPPLMNA | |
| SCHEMBL5748797 | 0.77 | — | — | |
| SCHEMBL30210557 | 0.77 | — | — | |
| SCHEMBL1979284 | 0.76 | AOC1 (0.61) | AOC1AOC3ALDH1A1KDM4ETDP1 | |
| SCHEMBL8047522 | 0.76 | AOC1 (0.61) | AOC1AOC3ALDH1A1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054865-A1 | FARNESYL TRANSFERASE INHIBITORS | AstraZeneca UK Limited (GB) | 2000-11-29 | — | — | EP | disclosed |
| WO-1999041235-A1 | FARNESYL TRANSFERASE INHIBITORS | ASTRAZENECA UK LIMITED (GB) | 1999-08-19 | — | — | WO | disclosed |