Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PAM | P19021 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL821433 | 0.93 | DGKA (0.52) | DGKAEPHX2ALDH1A1MEN1KMT2A | |
| SCHEMBL21659321 | 0.93 | EPHX2 (0.50) | DGKAEPHX2ALDH1A1MEN1KMT2A | |
| SCHEMBL12417283 | 0.93 | DGKA (0.59) | DGKAEPHX2ALDH1A1MAPTDNM1 | |
| SCHEMBL13751390 | 0.91 | DGKA (0.57) | DGKAEPHX2ALDH1A1MAPTDNM1 | |
| SCHEMBL14314266 | 0.89 | DGKA (0.53) | DGKAEPHX2ALDH1A1MEN1KMT2A | |
| SCHEMBL1532510 | 0.89 | DGKA (0.57) | DGKAEPHX2MEN1KMT2ATHRB | |
| SCHEMBL28474000 | 0.89 | DGKA (0.57) | DGKAEPHX2MEN1KMT2ATHRB | |
| SCHEMBL11108133 | 0.89 | DGKA (0.57) | DGKAEPHX2MEN1KMT2ATHRB | |
| SCHEMBL9003333 | 0.89 | DGKA (0.57) | DGKAEPHX2MEN1KMT2ATHRB | |
| SCHEMBL28736945 | 0.89 | DGKA (0.57) | DGKAEPHX2MEN1KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110287102-A1 | CHAIN EXTENDERS | POLYNOVO BIOMATERIALS PTY LIMITED (AU) | 2011-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110287102-A1 | CHAIN EXTENDERS | UMPS, PUF60, SMCHD1 | DGKA 1315/4885EPHX2 1813/4885ALDH1A1 333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.