Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 11/20 | 0.51 |
| ▸ | MME | P08473 | 10/20 | 0.51 |
| ▸ | CPA1 | P15085 | 8/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 8/20 | 0.51 |
| ▸ | ECE1 | P42892 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8896490 | 0.89 | ACE (0.41) | ACEMMECPA1ACE2ECE1 | |
| SCHEMBL29071842 | 0.88 | ACE (0.38) | ACEMMECPA1ACE2ECE1 | |
| SCHEMBL3810013 | 0.86 | CTRB1 (0.37) | ACEMMECPA1ACE2 | |
| SCHEMBL749821 | 0.86 | CTRB1 (0.37) | ACEMMECPA1ACE2 | |
| SCHEMBL9665720 | 0.86 | CTRB1 (0.37) | ACEMMECPA1ACE2 | |
| SCHEMBL749822 | 0.86 | CTRB1 (0.37) | ACEMMECPA1ACE2 | |
| SCHEMBL17293240 | 0.86 | CTRB1 (0.37) | ACEMMECPA1ACE2 | |
| SCHEMBL3916119 | 0.86 | CTRB1 (0.37) | ACEMMECPA1ACE2 | |
| SCHEMBL29511173 | 0.86 | CTRB1 (0.37) | ACEMMECPA1ACE2 | |
| SCHEMBL3916112 | 0.86 | CTRB1 (0.37) | ACEMMECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140786-A | ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1979-02-20 | — | — | US | claimed |
| US-6013798-A | WATER-BASED COMPOSITION FOR DECORATING SUBSTRATE, I.E., CERAMIC OR GLASS WITH BRIGHT GOLD FILM UPON FIRING COMPRISING A NON-RADIOACTIVE GOLD THIOLATE | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2000-01-11 | — | — | US | disclosed |
| US-5744245-A | POLYMERIC RESIN IN SOLUTION, WATER, COSOLVENT, AND THIOLATE OF PRECIOUS METAL | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 1998-04-28 | — | — | US | disclosed |
| EP-0514073-B1 | Precious metal composition | JOHNSON MATTHEY PLC (GB) | 1995-07-05 | — | — | EP | disclosed |
| US-5401535-A | Precious metal composition | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 1995-03-28 | — | — | US | disclosed |
| US-5281635-A | Polym,er resin and water-solvent solution of thiolate of platinum, palladium, gold, or silver for forming film on firing | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 1994-01-25 | — | — | US | disclosed |
| EP-0514073-A2 | Precious metal composition | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 1992-11-19 | — | — | EP | disclosed |