Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.41 |
| ▸ | ECE1 | P42892 | 10/20 | 0.39 |
| ▸ | MME | P08473 | 3/20 | 0.38 |
| ▸ | CPA1 | P15085 | 3/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP7 | P09237 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29071842 | 0.90 | ACE (0.38) | ACEECE1MMECPA1ACE2 | |
| SCHEMBL749822 | 0.89 | CTRB1 (0.37) | ACEMMECPA1ACE2 | |
| SCHEMBL29511173 | 0.89 | CTRB1 (0.37) | ACEMMECPA1ACE2 | |
| SCHEMBL3916112 | 0.89 | CTRB1 (0.37) | ACEMMECPA1ACE2 | |
| SCHEMBL3916119 | 0.89 | CTRB1 (0.37) | ACEMMECPA1ACE2 | |
| SCHEMBL749821 | 0.89 | CTRB1 (0.37) | ACEMMECPA1ACE2 | |
| SCHEMBL17293240 | 0.89 | CTRB1 (0.37) | ACEMMECPA1ACE2 | |
| SCHEMBL3810013 | 0.89 | CTRB1 (0.37) | ACEMMECPA1ACE2 | |
| SCHEMBL8216358 | 0.89 | ACE (0.51) | ACEECE1MMECPA1ACE2 | |
| SCHEMBL9665720 | 0.89 | CTRB1 (0.37) | ACEMMECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5620955-A | SYNTHETIC PEPTIDE DERIVATIVES; INHIBIT GROWTH OF SMALL CELL LUNG CANCER OR PANCREATIC CELLS | PEPTIDE TECHNOLOGIES CORPORATION (US) | 1997-04-15 | — | — | US | disclosed |
| WO-1995000542-A1 | BOMBESIN RECEPTOR ANTAGONISTS AND USES THEREOF | PEPTIDE TECHNOLOGIES CORPORATION (US) | 1995-01-05 | — | — | WO | disclosed |
| EP-0315367-A2 | Polypeptides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-05-10 | — | — | EP | disclosed |