SCHEMBL821656

SCHEMBL821656

[O]CCCCCCCCCCCCCC(=O)O

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.75
LMNA P02545 3/20 0.75
NFKB1 P19838 1/20 0.75
PMP22 Q01453 1/20 0.75
GPR84 Q9NQS5 8/20 0.60
FFAR1 O14842 2/20 0.60
FFAR4 Q5NUL3 2/20 0.60
SLC22A6 Q4U2R8 2/20 0.59
PPARG P37231 7/20 0.57
PPARD Q03181 7/20 0.57
PPARA Q07869 7/20 0.57
HDAC11 Q96DB2 5/20 0.57
ALDH1A1 P00352 3/20 0.57
PTPN1 P18031 3/20 0.57
TLR2 O60603 2/20 0.57
TDP1 Q9NUW8 2/20 0.57
MEN1 O00255 2/20 0.57
FABP4 P15090 2/20 0.57
ALOX15 P16050 2/20 0.57
KMT2A Q03164 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1006545 1.00 TSHR (0.75) TSHRLMNANFKB1PMP22GPR84
SCHEMBL1007211 1.00 TSHR (0.75) TSHRLMNANFKB1PMP22GPR84
SCHEMBL7553266 1.00 TSHR (0.75) TSHRLMNANFKB1PMP22GPR84
SCHEMBL95166 1.00 TSHR (0.75) TSHRLMNANFKB1PMP22GPR84
SCHEMBL95801 1.00
SCHEMBL1006395 1.00 TSHR (0.75) TSHRLMNANFKB1PMP22GPR84
SCHEMBL1006840 1.00 TSHR (0.75) TSHRLMNANFKB1PMP22GPR84
SCHEMBL1008881 1.00 TSHR (0.75) TSHRLMNANFKB1PMP22GPR84
SCHEMBL1008155 1.00 TSHR (0.75) TSHRLMNANFKB1PMP22GPR84
SCHEMBL1006815 1.00 TSHR (0.75) TSHRLMNANFKB1PMP22GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 261 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114041459-B Processing liquid for preserving natural primary colors of fresh cut camellia flowers and application thereof 云南欣绿茶花股份有限公司 2023-07-25 CN claimed
WO-2024126765-A1 RNAI-BASED THERAPIES TARGETING CLAUDIN-1 FOR THE TREATMENT AND PREVENTION OF FIBROTIC DISEASES UNIVERSITÉ DE STRASBOURG (FR) 2024-06-20 WO disclosed
EP-4362956-A1 LOW-MOLECULAR-WEIGHT HE800 EXOPOLYSACCHARIDE DERIVATIVES WITH ANTI-CANCER PROPERTIES AND USES THEREOF Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER) (FR) 2024-05-08 EP disclosed
US-20240116876-A1 SOCE Inhibitors and Therapeutic Uses Thereof Institut National de la Santé et de la Recherche Médicale (FR) 2024-04-11 US disclosed
US-20240099976-A1 BLENDED FORMULATIONS SEQUESSOME TECHNOLOGY HOLDINGS LIMITED (MT) 2024-03-28 US disclosed
CN-115053371-B Composite particle for electrochemical element, method for producing same, electrode for electrochemical element, and electrochemical element 日本瑞翁株式会社 2024-02-13 CN disclosed
US-11826399-B2 Chlorotoxin agents and uses thereof EISAI INC. (US) 2023-11-28 US disclosed
US-20230349922-A1 H2 Blockers Targeting Liver Macrophages for the Prevention and Treatment of Liver Disease and Cancer UNIVERSITÉ DE STRASBOURG (FR) 2023-11-02 US disclosed
EP-3289074-B1 CLINICAL GENE SIGNATURE-BASED HUMAN CELL CULTURE MODEL AND USES THEREOF UNIV STRASBOURG (FR) 2023-10-04 EP disclosed
US-20230233598-A1 Marine Bacterial Exopolysaccharide Derivatives and Uses Thereof in the Treatment of Mucopolysaccharidoses INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER (IFREMER) (FR) 2023-07-27 US disclosed
US-4670100-A Aqueous solutions or dispersions of polyisocyanate addition products, a process for their preparation, and their use as coating compounds or as sizing agents for paper BAYER AKTIENGESELLSCHAFT (DE) 1987-06-02 US disclosed
US-4636525-A NONIONIC SURFACTANT POLA CHEMICAL INDUSTRIES, INC. (JP) 1987-01-13 US disclosed
EP-0187806-A1 2-CHLORO-ETHYL PHOSPHONIC ACID ESTERS AND PLANT GROWTH REGULATING AGENTS CONTAINING SAME AS ACTIVE INGREDIENT NITROKEMIA IPARTELEPEK (HU) 1986-07-23 EP disclosed
US-4595537-A Containing aliphatic alcohol or fatty acid residue POLA CHEMICAL INDUSTRIES, INC. (JP) 1986-06-17 US disclosed
WO-1986000903-A1 2-CHLORO-ETHYL PHOSPHONIC ACID ESTERS AND PLANT GROWTH REGULATING AGENTS CONTAINING SAME AS ACTIVE INGREDIENT NITROKÉMIA IPARTELEPEK (HU) 1986-02-13 WO disclosed
EP-0049601-B1 SUNSCREEN COMPOSITIONS CONTAINING DELTA-5,7 STEROIDAL DIENES THE MASSACHUSETTS GENERAL HOSPITAL (US) 1985-03-27 EP disclosed
US-4332690-A GAS HYDRATE AND TETRABUTYLAMMONIUM SALT OR TETRAISOAMYLAMMONIUM SALT MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1982-06-01 US disclosed
EP-0049601-A2 Sunscreen compositions containing delta-5,7 steroidal dienes THE MASSACHUSETTS GENERAL HOSPITAL (US) 1982-04-14 EP disclosed
US-4310511-A Sunscreen compositions containing Δ5,7 steroidal dienes MASSACHUSETTS GENERAL HOSPITAL (US) 1982-01-12 US disclosed
US-3933662-A ALKALINE EARTH METAL CARBONATE, POLYOXYALKYLATED COMPOUNDS CHEVRON RESEARCH COMPANY (US) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240116876-A1 SOCE Inhibitors and Therapeutic Uses Thereof STIM1, ORAI1, STIM2 TSHR 2503/4885LMNA 2543/4885NFKB1 2138/4885
US-11826399-B2 Chlorotoxin agents and uses thereof NRP1, LCP1, CLSPN TSHR 2970/4885LMNA 4604/4885NFKB1 3091/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.