Chloromethane

Chloromethane

SCHEMBL8216574

CCl.CN(C)CC(O)COc1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.72

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Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 7/20 0.72
HIF1A Q16665 2/20 0.57
HTT P42858 2/20 0.57
MAPK1 P28482 3/20 0.56
ALDH1A1 P00352 3/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
CYP2D6 P10635 1/20 0.55
CYP2C9 P11712 1/20 0.55
CYP2C19 P33261 1/20 0.55
LMNA P02545 2/20 0.55
USP2 O75604 1/20 0.55
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
CDK4 P11802 1/20 0.52
HPGD P15428 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chloromethane SCHEMBL1132204 0.99 ABCB1 (0.70) ABCB1HIF1AHTTMAPK1ALDH1A1
SCHEMBL6552266 0.97 ABCB1 (0.76) ABCB1HIF1AHTTMAPK1ALDH1A1
Hydrochloric Acid SCHEMBL22228312 0.96 ABCB1 (0.74) ABCB1HIF1AHTTMAPK1ALDH1A1
SCHEMBL10313058 0.84 ABCB1 (0.64) ABCB1HTTMAPK1ALDH1A1SMN1; SMN2
SCHEMBL18543110 0.84 ABCB1 (0.71) ABCB1HTTMAPK1ALDH1A1SMN1; SMN2
SCHEMBL258823 0.82 HIF1A (0.75) ABCB1HIF1AHTTALDH1A1CYP2D6
Benzamide SCHEMBL4775810 0.82 HIF1A (0.58) ABCB1HIF1AHTTALDH1A1CDK4
SCHEMBL7898360 0.82 ABCB1 (0.53) ABCB1HIF1AHTTALDH1A1MEN1
SCHEMBL8926603 0.82 ABCB1 (0.69) ABCB1HTTMAPK1ALDH1A1SMN1; SMN2
SCHEMBL4197347 0.81 ABCB1 (0.68) ABCB1HTTMAPK1ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6140387-A RADIATING POLYVINYLCAPROLACTAM, POLYVINYL ETHER HOMO- OR COPOLYMERS,AN UNSATURATED COMPOUND, WATER AND/OR SOLVENT WITH HIGH-ENERGY LIGHT; SOLAR-ENERGY SYSTEMS; GLAZE BETWEEN WINDOW GLASS SHEETS; HEAT CONTROL; SWITCHES CLOUDINESS/CLARITY BASF AKTIENGESELLSCHAFT (DE) 2000-10-31 US disclosed