Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL419114 | 0.81 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2A | |
| SCHEMBL16657108 | 0.79 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2A | |
| SCHEMBL26478517 | 0.75 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2A | |
| SCHEMBL14587117 | 0.74 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2A | |
| SCHEMBL16021267 | 0.74 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2A | |
| SCHEMBL1930450 | 0.74 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2A | |
| SCHEMBL12190315 | 0.74 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2A | |
| SCHEMBL12493728 | 0.74 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2A | |
| SCHEMBL20825754 | 0.74 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2A | |
| SCHEMBL6958707 | 0.74 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008065503-A1 | (R) -5-METHYL-4, 5-DIHYDRO- PYRAZOLE-1, 5-DICARBOXYLIC ACID 1- [ ( 4 -CHLOROPHENYL) AMIDE 5-{ [2-FLUORO-4- (2-OXO-2H-PYRIDIN-1-YL) -PHENYL]AMIDE) AS A FACTOR XA INHIBITOR | PFIZER PRODUCTS INC. (US) | 2008-06-05 | — | — | WO | disclosed |