Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.75 |
| ▸ | THRB | P10828 | 1/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Amino-4-Nitrophenol SCHEMBL31297314 | 0.87 | GAA (1.00) | GAATHRBTDP1ALDH1A1CYP3A4 | |
| 2-Amino-4-Nitrophenol SCHEMBL22943 | 0.87 | GAA (1.00) | GAATHRBTDP1ALDH1A1CYP3A4 | |
| 2-Amino-4-Nitrophenol SCHEMBL6894960 | 0.85 | GAA (0.96) | GAATHRBTDP1ALDH1A1CYP3A4 | |
| 2-Amino-4-Nitrophenol SCHEMBL19950746 | 0.85 | GAA (0.96) | GAATHRBTDP1ALDH1A1CYP3A4 | |
| 2-Amino-4-Nitrophenol SCHEMBL31193638 | 0.85 | GAA (0.96) | GAATHRBTDP1ALDH1A1CYP3A4 | |
| 2-Amino-4-Nitrophenol SCHEMBL11137165 | 0.85 | GAA (0.96) | GAATHRBTDP1ALDH1A1CYP3A4 | |
| 2-Amino-4-Nitrophenol SCHEMBL19950506 | 0.85 | GAA (0.96) | GAATHRBTDP1ALDH1A1CYP3A4 | |
| 2-Amino-4-Nitrophenol SCHEMBL6894954 | 0.85 | GAA (0.96) | GAATHRBTDP1ALDH1A1CYP3A4 | |
| 2-Amino-4-Nitrophenol SCHEMBL19950745 | 0.85 | GAA (0.96) | GAATHRBTDP1ALDH1A1CYP3A4 | |
| 2-Amino-4-Nitrophenol SCHEMBL19950749 | 0.85 | GAA (0.96) | GAATHRBTDP1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019720-A1 | COMBINATORIAL PROCESS FOR PREPARING TETRAHYDROQUINOLINE LIBRARIES | ELI LILLY AND COMPANY (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1998027427-A1 | COMBINATORIAL PROCESS FOR PREPARING TETRAHYDROQUINOLINE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-06-25 | — | — | WO | disclosed |