Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.40 |
| ▸ | RARA | P10276 | 2/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8215809 | 0.92 | RARB (0.34) | RARBRARARARGHTR2AHTR2C | |
| SCHEMBL8219129 | 0.92 | RARB (0.34) | RARBRARARARGHTR2AHTR2C | |
| SCHEMBL7024851 | 0.89 | RARB (0.41) | RARBRARARARGS1PR1GPR84 | |
| SCHEMBL7024857 | 0.85 | RARB (0.44) | RARBRARARARGS1PR1GPR84 | |
| SCHEMBL8215078 | 0.83 | RARB (0.43) | RARBRARARARGS1PR1GPR84 | |
| SCHEMBL7916265 | 0.83 | RARB (0.40) | RARBRARARARGS1PR1HTR2A | |
| SCHEMBL7916260 | 0.83 | RARB (0.40) | RARBRARARARGS1PR1HTR2A | |
| SCHEMBL7916257 | 0.83 | RARB (0.40) | RARBRARARARGS1PR1HTR2A | |
| SCHEMBL7916263 | 0.83 | RARB (0.40) | RARBRARARARGS1PR1HTR2A | |
| SCHEMBL8816486 | 0.82 | RARB (0.47) | RARBRARARARGGPR84TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117361-A | FOUR RING COMPOUND HAVING AN ALKYL GROUP SUBSTITUTED WITH ONE OR MORE ETHERS, AND A HALOGEN ATOM SUBSTITUTED BENZENE RING; BROAD TEMPERATURE RANGE OF NEMATIC PHASE, HIGHER MISCIBILITY WITH OTHER LIQUID CRYSTAL COMPOUNDS, AND CHEMICAL STABILITY | CHISSO CORP. (JP) | 2000-09-12 | — | — | US | disclosed |
| EP-0891961-A1 | LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED 1,4-PHENYLENE SKELETONS, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES | CHISSO CORPORATION (JP) | 1999-01-20 | — | — | EP | disclosed |