SCHEMBL821700

SCHEMBL821700

C=C(NC=CC(=O)O)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
TP53 P04637 1/20 0.38
EGLN1 Q9GZT9 1/20 0.38
EGLN3 Q9H6Z9 1/20 0.38
ALOX15 P16050 1/20 0.33
HSD17B10 Q99714 1/20 0.33
HCAR2 Q8TDS4 1/20 0.32
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18044384 0.73
SCHEMBL551867 0.71 TGFBR1 (0.35) TSHRTP53EGLN1EGLN3ALOX15
SCHEMBL7058771 0.70
SCHEMBL26085 0.70 LMNA (0.43) TSHRTP53EGLN1EGLN3ALOX15
SCHEMBL1871042 0.69
SCHEMBL5610740 0.69
SCHEMBL11772373 0.69
SCHEMBL18956906 0.69
SCHEMBL5610743 0.69
SCHEMBL1274398 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7968197-B2 Polyurea coating comprising an amine/(meth)acrylate oligomeric reaction product PPG INDUSTRIES OHIO, INC. (US) 2011-06-28 US disclosed
EP-2097466-B1 POLYUREA COATING COMPRISING AN AMINE/(METH)ACRYLATE OLIGOMERIC REACTION PRODUCT PPG IND OHIO INC (US) 2010-05-26 EP disclosed
EP-2097466-A2 POLYUREA COATING COMPRISING AN AMINE/(METH)ACRYLATE OLIGOMERIC REACTION PRODUCT PPG Industries Ohio, Inc. (US) 2009-09-09 EP disclosed
WO-2008076662-A2 POLYUREA COATING COMPRISING AN AMINE/(METH)ACRYLATE OLIGOMERIC REACTION PRODUCT PPG INDUSTRIES OHIO, INC. (US) 2008-06-26 WO disclosed
US-20070160851-A1 POLYUREA COATING COMPRISING AN AMINE/(METH)ACRYLATE OLIGOMERIC REACTION PRODUCT PPG INDUSTRIES OHIO, INC. 2007-07-12 US disclosed