Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.36 |
| ▸ | HTR1A | P08908 | 3/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | FHIT | P49789 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6167914 | 0.82 | HPGD (0.42) | S1PR1ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL6029996 | 0.81 | PTGES (0.40) | HTR1AMEN1ALDH1A1KMT2ANPC1 | |
| Ethane SCHEMBL6029074 | 0.80 | PTGES (0.39) | HTR1AMEN1ALDH1A1KMT2ANPC1 | |
| SCHEMBL29660392 | 0.80 | HTR2A (0.41) | ADRA1AMEN1ALDH1A1KMT2ANPC1 | |
| SCHEMBL6168691 | 0.80 | HTR2A (0.41) | ADRA1AMEN1ALDH1A1KMT2ANPC1 | |
| SCHEMBL24575397 | 0.79 | HTT (0.35) | KMT2AKDM4E | |
| SCHEMBL6029078 | 0.79 | PTPN11 (0.42) | HTR1AALDH1A1KDM4EHPGD | |
| SCHEMBL22102585 | 0.76 | HTR2C (0.41) | ADRA1AALDH1A1NPC1HTR2CHTR2B | |
| SCHEMBL22802353 | 0.71 | RXRB (0.49) | SLC6A4L3MBTL1 | |
| SCHEMBL8195029 | 0.69 | MEN1 (0.43) | CXCR2MEN1ALDH1A1KMT2AFGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000078724-A2 | IMIDAZOLINDERIVATIVES THEIR PREPARATION AND THEIR PHARMACEUTICAL USE | ELI LILLY AND COMPANY (US) | 2000-12-28 | — | — | WO | disclosed |