Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14574573 | 0.78 | MEN1 (0.39) | MEN1KMT2AFGFR4DRD1DRD3 | |
| SCHEMBL8194455 | 0.77 | ALDH1A1 (0.35) | FGFR4DRD1DRD3ALDH1A1EGFR | |
| SCHEMBL11626183 | 0.72 | MEN1 (0.50) | MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL11866795 | 0.71 | MEN1 (0.49) | MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL8208937 | 0.70 | PDCD1LG2 (0.35) | PARP1 | |
| SCHEMBL8382228 | 0.70 | PRKDC (0.42) | LMNAALDH1A1CYP1A2CYP2C19EGFR | |
| SCHEMBL11626605 | 0.69 | MEN1 (0.64) | MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL8217052 | 0.69 | SLC6A4 (0.36) | MEN1KMT2AFGFR4CXCR2ALDH1A1 | |
| SCHEMBL11625348 | 0.69 | MEN1 (0.52) | MEN1KMT2ALMNAALDH1A1CYP1A2 | |
| SCHEMBL11629337 | 0.69 | MEN1 (0.56) | MEN1KMT2ALMNAALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000078724-A2 | IMIDAZOLINDERIVATIVES THEIR PREPARATION AND THEIR PHARMACEUTICAL USE | ELI LILLY AND COMPANY (US) | 2000-12-28 | — | — | WO | disclosed |