Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 5/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | DRD4 | P21917 | 3/20 | 0.39 |
| ▸ | DRD3 | P35462 | 3/20 | 0.39 |
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7969716 | 0.88 | HTR7 (0.59) | HTR7ADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL27605028 | 0.82 | HTR7 (0.42) | HTR7ADRA1DADRA1AADRA1BLMNA | |
| SCHEMBL7970120 | 0.82 | HTR7 (0.47) | HTR7ADRA1DADRA1AADRA1BLMNA | |
| SCHEMBL7956908 | 0.82 | HTR7 (0.42) | HTR7ADRA1DADRA1AADRA1B | |
| SCHEMBL27511379 | 0.81 | HTR7 (0.47) | HTR7ADRA1DADRA1AADRA1BLMNA | |
| SCHEMBL8256396 | 0.78 | HTR7 (0.58) | HTR7ADRA1DADRA1AADRA1BLMNA | |
| SCHEMBL9300436 | 0.77 | SCN9A (0.45) | HTR7ADRA1DADRA1AADRA1BLMNA | |
| SCHEMBL7126204 | 0.71 | HTR7 (0.50) | HTR7ADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL32675860 | 0.70 | HTR7 (0.69) | HTR7ADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL32675853 | 0.70 | HTR7 (0.73) | HTR7ADRA1DADRA1AADRA1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000078737-A2 | ARYLOXY ETHYLAMINO TRIAZINES AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-28 | — | — | WO | disclosed |
| WO-2000034437-A2 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2000-06-15 | — | — | WO | disclosed |