Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 9/20 | 0.58 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.58 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | IDH2 | P48735 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7969716 | 0.90 | HTR7 (0.59) | HTR7ADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL32675853 | 0.86 | HTR7 (0.73) | HTR7ADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL32675860 | 0.86 | HTR7 (0.69) | HTR7ADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL8021955 | 0.80 | HTR7 (0.53) | HTR7TSHRALDH1A1HPGDLMNA | |
| SCHEMBL8217064 | 0.78 | HTR7 (0.49) | HTR7ADRA1DADRA1AADRA1BTSHR | |
| SCHEMBL11819405 | 0.77 | NPSR1 (0.59) | TSHR | |
| SCHEMBL27511379 | 0.77 | HTR7 (0.47) | HTR7ADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL7155922 | 0.76 | HTR7 (0.60) | HTR7ADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL8070478 | 0.74 | TSHR (0.43) | HTR7ADRA1DADRA1AADRA1BTSHR | |
| SCHEMBL9300436 | 0.74 | SCN9A (0.45) | HTR7ADRA1DADRA1AADRA1BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000078737-A2 | ARYLOXY ETHYLAMINO TRIAZINES AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-28 | — | — | WO | disclosed |