Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10352835 | 0.77 | RIPK1 (0.50) | KMT2AMEN1NPC1RAB9ACA12 | |
| SCHEMBL11051641 | 0.75 | MAPT (0.40) | KMT2AMEN1TSHRALDH1A1OPRK1 | |
| SCHEMBL4628462 | 0.73 | KMT2A (0.51) | KMT2AMEN1NPC1RAB9ACA12 | |
| SCHEMBL7195198 | 0.71 | AKT1 (0.43) | KMT2AMEN1NPC1RAB9ACA12 | |
| SCHEMBL6158106 | 0.69 | SMN1; SMN2 (0.48) | HPGDKMT2AMEN1NPC1RAB9A | |
| SCHEMBL28273624 | 0.69 | TSHR (0.56) | NPC1RAB9ACA12CA9TSHR | |
| SCHEMBL31481619 | 0.69 | TSHR (0.56) | KMT2AMEN1NPC1RAB9ACA12 | |
| SCHEMBL27138796 | 0.69 | RIPK1 (0.47) | KMT2AMEN1NPC1RAB9ACA12 | |
| SCHEMBL10889783 | 0.69 | RIPK1 (0.47) | KMT2AMEN1NPC1RAB9ACA12 | |
| SCHEMBL28997309 | 0.68 | HIF1A (0.52) | KMT2AMEN1NPC1RAB9ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0956033-A4 | TOTAL SYNTHESIS OF THE AMINO HIP ANALOGUE OF DIDEMNIN A | UNIV ILLINOIS (US) | 2000-06-21 | — | — | EP | disclosed |
| EP-0956033-A1 | TOTAL SYNTHESIS OF THE AMINO HIP ANALOGUE OF DIDEMNIN A | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 1999-11-17 | — | — | EP | disclosed |
| WO-1998017302-A1 | TOTAL SYNTHESIS OF THE AMINO HIP ANALOGUE OF DIDEMNIN A | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 1998-04-30 | — | — | WO | disclosed |