Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11052172 | 0.83 | ALDH1A1 (0.41) | MAPTSMN1; SMN2LMNAALDH1A1TP53 | |
| SCHEMBL11076701 | 0.78 | HTT (0.49) | MAPTSMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL8217458 | 0.75 | HPGD (0.46) | ALDH1A1KCNH2OPRK1KMT2AMEN1 | |
| SCHEMBL11052732 | 0.74 | KMT2A (0.46) | MAPTSMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL2170767 | 0.72 | MAPT (0.37) | MAPTSMN1; SMN2ALDH1A1GRIN2DGRIN1 | |
| SCHEMBL27693748 | 0.71 | MAPT (0.38) | MAPTSMN1; SMN2LMNAALDH1A1TP53 | |
| Lithium SCHEMBL7357936 | 0.69 | GRM2 (0.30) | — | |
| SCHEMBL7357927 | 0.69 | GRM2 (0.30) | — | |
| SCHEMBL4289552 | 0.68 | MAPT (0.41) | MAPTSMN1; SMN2LMNAALDH1A1TP53 | |
| SCHEMBL13740317 | 0.67 | CHRM3 (0.58) | MAPTSMN1; SMN2LMNAGAACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443474-A | ANTICONVULSANT, ADMINISTERING | BUFFALO COLOR CORPORATION (US) | 1984-04-17 | — | — | US | claimed |
| US-4443474-A | ANTICONVULSANT, ADMINISTERING | BUFFALO COLOR CORPORATION (US) | 1984-04-17 | — | — | US | disclosed |