Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8217143 | 0.78 | KDM4E (0.41) | KDM4EHPGDSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL8220669 | 0.76 | BCHE (0.35) | LMNAMAPT | |
| SCHEMBL9424730 | 0.75 | TLR8 (0.44) | KDM4EHPGDSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL9375754 | 0.72 | SOAT1 (0.47) | KDM4EHPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL14656851 | 0.71 | CYP19A1 (0.48) | L3MBTL1 | |
| SCHEMBL8216677 | 0.69 | XDH (0.55) | KDM4EHPGDSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL8353233 | 0.68 | ADORA1 (0.44) | ALDH1A1MEN1MAPK1KMT2A | |
| Hydrochloric Acid SCHEMBL10849379 | 0.67 | MEN1 (0.51) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10852051 | 0.67 | MEN1 (0.51) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8682869 | 0.65 | KDM4E (0.59) | KDM4EHPGDSMN1; SMN2ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000006552-A1 | 4-PHENYL- AND 4,5-DIPHENYLIMIDAZOLE DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATION | SANOFI-SYNTHELABO (FR) | 2000-02-10 | — | — | WO | disclosed |