Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | PI4KA | P42356 | 2/20 | 0.47 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.47 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1927931 | 0.76 | MAPK13 (0.48) | SMN1; SMN2KDM4EHPGDLMNAALDH1A1 | |
| SCHEMBL8682869 | 0.76 | KDM4E (0.59) | XDHSMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL17550122 | 0.76 | BRD4 (0.72) | XDHSMN1; SMN2MEN1POLBKMT2A | |
| SCHEMBL9424730 | 0.75 | TLR8 (0.44) | SMN1; SMN2PIM1KDM4EHPGDLMNA | |
| SCHEMBL4713021 | 0.72 | KDM4E (0.50) | XDHSMN1; SMN2RAB9AMEN1POLB | |
| SCHEMBL9375754 | 0.72 | SOAT1 (0.47) | SMN1; SMN2RAB9AKDM4EHPGDALDH1A1 | |
| SCHEMBL3278317 | 0.71 | KDM4E (0.58) | SMN1; SMN2KMT2AKDM4EHPGDLMNA | |
| SCHEMBL3593419 | 0.70 | RAB9A (1.00) | SMN1; SMN2RAB9ATP53MEN1POLB | |
| SCHEMBL31329340 | 0.70 | RAB9A (1.00) | SMN1; SMN2RAB9ATP53MEN1POLB | |
| SCHEMBL1927301 | 0.70 | KDM4E (0.55) | SMN1; SMN2KDM4EHPGDLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103044337-A | Synthetic method of 2-(N-alkyl)aminooimidazole derivatives | UNIV NANJING SCIENCE & TECH | 2013-04-17 | — | — | CN | disclosed |
| WO-2000006552-A1 | 4-PHENYL- AND 4,5-DIPHENYLIMIDAZOLE DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATION | SANOFI-SYNTHELABO (FR) | 2000-02-10 | — | — | WO | disclosed |