Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23328518 | 0.78 | AKT1 (0.56) | ALDH1A1AKT1MAPTMEN1KMT2A | |
| SCHEMBL313871 | 0.78 | AKT1 (0.56) | ALDH1A1AKT1MAPTMEN1KMT2A | |
| SCHEMBL3281298 | 0.78 | ALDH1A1 (0.56) | ALDH1A1MAPTMAOAMAOBEGFR | |
| SCHEMBL13974486 | 0.77 | AKT1 (0.39) | ALDH1A1AKT1MAPTLMNAMAOA | |
| SCHEMBL14361165 | 0.74 | AKT1 (0.48) | ALDH1A1AKT1MAPTMEN1KMT2A | |
| SCHEMBL19959687 | 0.72 | AKT1 (0.46) | ALDH1A1AKT1MAPTMEN1KMT2A | |
| SCHEMBL29175028 | 0.72 | AKT1 (0.46) | ALDH1A1AKT1MAPTMEN1KMT2A | |
| SCHEMBL26209223 | 0.72 | ALDH1A1 (0.35) | ALDH1A1AKT1MAPTLMNAMAOA | |
| SCHEMBL7802784 | 0.72 | AKT1 (0.42) | ALDH1A1AKT1MAPTLMNAEGFR | |
| SCHEMBL6306447 | 0.72 | ALDH1A1 (0.50) | ALDH1A1MAPTMAOAMAOBEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998021521-A9 | TWO-PHOTON OR HIGHER-ORDER ABSORBING OPTICAL MATERIALS AND METHODS OF USE | CALIFORNIA INST OF TECHN (US) | 2000-03-02 | — | — | WO | disclosed |
| WO-1998021521-A1 | TWO-PHOTON OR HIGHER-ORDER ABSORBING OPTICAL MATERIALS AND METHODS OF USE | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1998-05-22 | — | — | WO | disclosed |