Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2657412 | 0.76 | POLB (0.31) | — | |
| SCHEMBL8217572 | 0.69 | — | — | |
| SCHEMBL1768267 | 0.69 | — | — | |
| SCHEMBL1768196 | 0.66 | — | — | |
| SCHEMBL11947847 | 0.64 | TDP1 (0.35) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL15892803 | 0.63 | PGD (0.33) | — | |
| SCHEMBL8271289 | 0.61 | HTR1A (0.33) | SIGMAR1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL82090 | 0.60 | — | — | |
| SCHEMBL28411820 | 0.59 | SYK (0.38) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL996217 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000023444-A1 | 5,7-DISUBSTITUTED-4-AMINOPYRIDO[2,3-D]PYRIMIDINE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-04-27 | — | — | WO | disclosed |