SCHEMBL8218091

SCHEMBL8218091

C=C1CCN(S(=O)(=O)c2ccc(N)cc2)CC1

nearest known ligand 0.68

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PKM P14618 6/20 0.54
KMT2A Q03164 2/20 0.50
USP2 O75604 1/20 0.50
MEN1 O00255 1/20 0.50
MMP2 P08253 1/20 0.47
GCK P35557 1/20 0.45
ALDH1A1 P00352 1/20 0.44
TSHR P16473 1/20 0.44
NT5E P21589 1/20 0.44
CD4 P01730 2/20 0.43
NPC1 O15118 1/20 0.43
PKLR P30613 1/20 0.43
RAB9A P51151 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11306227 0.85 PKM (0.69) PKMKMT2AUSP2MEN1MMP2
SCHEMBL13548367 0.82 PKM (0.66) PKMKMT2AMEN1ALDH1A1TSHR
SCHEMBL8217521 0.82 PKM (0.64) PKMKMT2AUSP2MEN1ALDH1A1
SCHEMBL13548567 0.82 KMT2A (0.72) PKMKMT2AUSP2MEN1ALDH1A1
SCHEMBL8220170 0.81 GAA (0.62) PKMKMT2AMEN1ALDH1A1TSHR
SCHEMBL78283 0.81 USP2 (0.69) PKMKMT2AUSP2MEN1MMP2
SCHEMBL655768 0.81 USP2 (0.76) PKMKMT2AUSP2MEN1ALDH1A1
SCHEMBL8211579 0.80 PKM (0.61) PKMKMT2AMEN1GCKALDH1A1
SCHEMBL3690418 0.79 USP2 (0.80) PKMKMT2AUSP2MEN1ALDH1A1
SCHEMBL165129 0.79 USP2 (0.80) PKMKMT2AUSP2MEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008008398-A2 OXIME COMPOUNDS AND THE USE THEREOF SHIONOGI & CO., LTD. (JP) 2008-01-17 WO disclosed