Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3830424 | 0.83 | POLB (0.80) | GAAPOLBPKMALDH1A1LMNA | |
| SCHEMBL7122592 | 0.83 | POLB (0.80) | GAAPOLBPKMALDH1A1LMNA | |
| SCHEMBL735657 | 0.83 | POLB (0.80) | GAAPOLBPKMALDH1A1LMNA | |
| SCHEMBL3918890 | 0.82 | KMT2A (0.68) | GAAPOLBMEN1KMT2APKM | |
| SCHEMBL13548367 | 0.81 | PKM (0.66) | GAAPOLBMEN1KMT2APKM | |
| SCHEMBL8217521 | 0.81 | PKM (0.64) | POLBMEN1KMT2APKMALDH1A1 | |
| SCHEMBL13548567 | 0.81 | KMT2A (0.72) | POLBMEN1KMT2APKMALDH1A1 | |
| SCHEMBL8218091 | 0.81 | PKM (0.54) | MEN1KMT2APKMALDH1A1TSHR | |
| SCHEMBL4526586 | 0.80 | POLB (0.69) | GAAPOLBPKMALDH1A1LMNA | |
| SCHEMBL8211579 | 0.80 | PKM (0.61) | GAAMEN1KMT2APKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008008398-A2 | OXIME COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2008-01-17 | — | — | WO | disclosed |