Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 2/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | NOS2 | P35228 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | NT5E | P21589 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8218500 | 0.88 | CYP17A1 (0.36) | PLGNOS3NOS1NOS2NAMPT | |
| SCHEMBL8200238 | 0.79 | PLG (0.40) | PLGNOS3NOS1NOS2GAA | |
| SCHEMBL504667 | 0.72 | PLG (0.44) | PLGNOS3NOS1NOS2 | |
| SCHEMBL504588 | 0.72 | PLG (0.44) | PLGNOS3NOS1NOS2 | |
| SCHEMBL9299302 | 0.70 | PLG (0.42) | PLGNOS3NOS1NOS2KDM4E | |
| SCHEMBL504564 | 0.69 | PLG (0.41) | PLGNOS3NOS1NOS2F2 | |
| SCHEMBL8200233 | 0.68 | CYP17A1 (0.45) | PLGNOS3NOS1NOS2ALDH1A1 | |
| SCHEMBL2351953 | 0.60 | KMT2A (0.71) | GAALMNATSHRTDP1L3MBTL1 | |
| SCHEMBL5745307 | 0.60 | GAA (0.55) | GAAF2PRSS1PRSS2PRSS3 | |
| SCHEMBL7082360 | 0.59 | CYP3A4 (0.47) | GAALMNAAGO2TSHRNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000061561-A1 | CYANOGUANIDINE COMPOUNDS | SHIONOGI BIORESEARCH CORP. (US) | 2000-10-19 | — | — | WO | disclosed |