Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GCGR | P47871 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8746387 | 0.90 | PTPN11 (0.42) | SMN1; SMN2 | |
| SCHEMBL8450272 | 0.90 | PTPN11 (0.42) | SMN1; SMN2 | |
| SCHEMBL1242253 | 0.89 | FGFR2 (0.40) | HPGDMAPTALDH1A1KDM4ELMNA | |
| SCHEMBL22926384 | 0.86 | MAPT (0.38) | HPGDMAPTALDH1A1KDM4ERAB9A | |
| SCHEMBL24122299 | 0.84 | MAPT (0.38) | HPGDMAPTALDH1A1KDM4ERAB9A | |
| SCHEMBL25693797 | 0.84 | CSNK2A1 (0.39) | MAPTALDH1A1KDM4EGCGRSMN1; SMN2 | |
| SCHEMBL883358 | 0.84 | GAA (0.47) | MAPTALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL16855902 | 0.84 | CCNT1 (0.38) | MAPTALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL15684600 | 0.84 | ADRB2 (0.46) | MAPTALDH1A1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL9494314 | 0.83 | TDP1 (0.43) | MAPTALDH1A1KDM4ENPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0982387-A1 | Liquid crystal compound having negative dielectric anisotropy, liquid crystal composition containing said liquid crystal compound and liquid crystal display device using said composition | Chisso Corporation (JP) | 2000-03-01 | — | — | EP | disclosed |