SCHEMBL883358

SCHEMBL883358

CCCOc1ccc(-c2ccc(O)cc2)c(F)c1F

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 6/20 0.47
▸ MGAM O43451 5/20 0.47
▸ SI P14410 5/20 0.47
▸ MGAM2 Q2M2H8 5/20 0.47
▸ LTA4H P09960 4/20 0.44
▸ ESR1 P03372 5/20 0.37
▸ GABRA1 P14867 1/20 0.37
▸ GABRB2 P47870 1/20 0.37
▸ NR5A1 Q13285 1/20 0.37
▸ ALDH1A1 P00352 2/20 0.36
▸ CHRM1 P11229 1/20 0.36
▸ TSHR P16473 1/20 0.36
▸ SLC6A2 P23975 1/20 0.36
▸ KDR P35968 1/20 0.36
▸ TDP1 Q9NUW8 1/20 0.36
▸ USP7 Q93009 2/20 0.35
▸ FPR2 P25090 1/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ USP2 O75604 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8993242 0.90 NR5A1 (0.51) LTA4HESR1NR5A1ALDH1A1CHRM1
SCHEMBL4866836 0.90 NR5A1 (0.51) LTA4HESR1NR5A1ALDH1A1CHRM1
SCHEMBL21609931 0.89 LTA4H (0.42) GAAMGAMSIMGAM2LTA4H
SCHEMBL4867877 0.88 NR5A1 (0.50) LTA4HESR1NR5A1ALDH1A1CHRM1
SCHEMBL22926384 0.86 MAPT (0.38) GAAMGAMSIMGAM2GABRA1
SCHEMBL24122299 0.84 MAPT (0.38) GAAMGAMSIMGAM2GABRA1
SCHEMBL25693797 0.84 CSNK2A1 (0.39) GAAMGAMSIMGAM2GABRA1
SCHEMBL8218560 0.84 HPGD (0.42) GAAMGAMSIMGAM2GABRA1
SCHEMBL15684600 0.84 ADRB2 (0.46) GAAALDH1A1TDP1FPR2KDM4E
SCHEMBL3035778 0.84 LPL (0.37) GAAMGAMSIMGAM2GABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3660130-B1 LIQUID CRYSTAL DISPLAYS AND LIQUID CRYSTALLINE MEDIA WITH HOMEOTROPIC ALIGNMENT MERCK PATENT GMBH (DE) 2021-08-04 — — EP disclosed
US-11015121-B2 Liquid crystal displays and liquid crystalline media with homeotropic alignment MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2021-05-25 — — US disclosed
US-10747061-B2 Display device SAMSUNG DISPLAY CO., LTD. (KR) 2020-08-18 — — US disclosed
EP-3660130-A1 LIQUID CRYSTAL DISPLAYS AND LIQUID CRYSTALLINE MEDIA WITH HOMEOTROPIC ALIGNMENT Merck Patent GmbH (DE) 2020-06-03 — — EP disclosed
US-20190271886-A1 CURVED LIQUID CRYSTAL DISPLAY DEVICE SAMSUNG DISPLAY CO LTD (KR) 2019-09-05 — — US disclosed
US-20190256771-A1 LIQUID CRYSTAL DISPLAYS AND LIQUID CRYSTALLINE MEDIA WITH HOMEOTROPIC ALIGNMENT MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2019-08-22 — — US disclosed
US-10338436-B2 Method of manufacturing curved liquid crystal display device and curved liquid crystal display device SAMSUNG DISPLAY CO., LTD. (KR) 2019-07-02 — — US disclosed
US-10273409-B2 Liquid crystal displays and liquid crystalline media with homeotropic alignment MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2019-04-30 — — US disclosed
US-20180120647-A1 DISPLAY DEVICE TCL CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2018-05-03 — — US disclosed
US-20180120647-A1 DISPLAY DEVICE TCL CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2018-05-03 — — US disclosed
US-20180022997-A1 LIQUID CRYSTAL DISPLAYS AND LIQUID CRYSTALLINE MEDIA WITH HOMEOTROPIC ALIGNMENT MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2018-01-25 — — US disclosed
US-9868904-B2 Liquid crystal displays and liquid crystalline media with homeotropic alignment MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2018-01-16 — — US disclosed
US-9868904-B2 Liquid crystal displays and liquid crystalline media with homeotropic alignment MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2018-01-16 — — US disclosed
EP-3211059-A1 LIQUID CRYSTAL DISPLAYS AND LIQUID CRYSTALLINE MEDIA WITH HOMEOTROPIC ALIGNMENT Merck Patent GmbH (DE) 2017-08-30 — — EP disclosed
EP-2619284-B1 LIQUID CRYSTAL DISPLAYS AND LIQUID CRYSTALLINE MEDIA WITH HOMEOTROPIC ALIGNMENT MERCK PATENT GMBH (DE) 2017-04-12 — — EP disclosed
US-20160147116-A1 LIQUID CRYSTAL DISPLAY AND MANUFACTURING METHOD THEREOF SAMSUNG DISPLAY CO., LTD. (KR) 2016-05-26 — — US disclosed
US-20160147116-A1 LIQUID CRYSTAL DISPLAY AND MANUFACTURING METHOD THEREOF SAMSUNG DISPLAY CO., LTD. (KR) 2016-05-26 — — US disclosed
US-20130182202-A1 LIQUID CRYSTAL DISPLAYS AND LIQUID CRYSTALLINE MEDIA WITH HOMEOTROPIC ALIGNMENT MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2013-07-18 — — US disclosed
US-20130182202-A1 LIQUID CRYSTAL DISPLAYS AND LIQUID CRYSTALLINE MEDIA WITH HOMEOTROPIC ALIGNMENT MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2013-07-18 — — US disclosed
WO-2012038026-A1 LIQUID CRYSTAL DISPLAYS AND LIQUID CRYSTALLINE MEDIA WITH HOMEOTROPIC ALIGNMENT MERCK PATENT GMBH (DE) 2012-03-29 — — WO disclosed
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