SCHEMBL821857

SCHEMBL821857

CCCCC(O)COC(=O)CCC(=O)OCC(O)CCCC

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.61
KDM4E B2RXH2 1/20 0.61
DUSP3 P51452 1/20 0.61
MEN1 O00255 1/20 0.61
KMT2A Q03164 1/20 0.61
CYP3A4 P08684 1/20 0.58
TSHR P16473 1/20 0.58
ATM Q13315 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
MAPT P10636 1/20 0.55
LPAR1 Q92633 5/20 0.53
ENPP2 Q13822 4/20 0.53
LPAR4 Q99677 2/20 0.53
LPAR2 Q9HBW0 2/20 0.53
LPAR3 Q9UBY5 2/20 0.53
LPAR6 P43657 1/20 0.53
LPAR5 Q9H1C0 1/20 0.53
DGKA P23743 1/20 0.51
FAAH O00519 2/20 0.49
TRPV1 Q8NER1 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23926205 0.94 LMNA (0.64) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL30313729 0.94 LMNA (0.59) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL20772709 0.94 LMNA (0.69) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL822170 0.92 LMNA (0.67) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL821605 0.92 LMNA (0.67) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL28901086 0.91 LMNA (0.75) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL8570716 0.88 KDM4E (0.51) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL19814956 0.88 LMNA (0.57) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL15512207 0.88 LMNA (0.61) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL22028541 0.88 LMNA (0.55) LMNAKDM4EDUSP3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11155675-B2 Method of regioselective synthesis of polyesters from asymmetric diols VERSALIS S.P.A. (IT) 2021-10-26 US disclosed
CN-109689727-B Process for the regioselective synthesis of polyesters from asymmetric diols 维尔萨利斯股份公司 2020-12-01 CN disclosed
EP-3491044-B1 METHOD OF REGIOSELECTIVE SYNTHESIS OF POLYESTERS FROM ASYMMETRIC DIOLS VERSALIS SPA (IT) 2020-08-26 EP disclosed
US-20200181319-A1 METHOD OF REGIOSELECTIVE SYNTHESIS OF POLYESTERS FROM ASYMMETRIC DIOLS VERSALIS S.P.A. (IT) 2020-06-11 US disclosed
US-20110287102-A1 CHAIN EXTENDERS POLYNOVO BIOMATERIALS PTY LIMITED (AU) 2011-11-24 US disclosed
US-20110287102-A1 CHAIN EXTENDERS POLYNOVO BIOMATERIALS PTY LIMITED (AU) 2011-11-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110287102-A1 CHAIN EXTENDERS UMPS, PUF60, SMCHD1 LMNA 570/4885KDM4E 1903/4885DUSP3 4733/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.