Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CETP | P11597 | 3/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8221381 | 1.00 | ALDH1A1 (0.44) | ALDH1A1MEN1HPGDKMT2ACETP | |
| SCHEMBL8221385 | 1.00 | ALDH1A1 (0.44) | ALDH1A1MEN1HPGDKMT2ACETP | |
| SCHEMBL8218572 | 1.00 | ALDH1A1 (0.44) | ALDH1A1MEN1HPGDKMT2ACETP | |
| SCHEMBL8218717 | 1.00 | ALDH1A1 (0.44) | ALDH1A1MEN1HPGDKMT2ACETP | |
| SCHEMBL8218720 | 1.00 | ALDH1A1 (0.44) | ALDH1A1MEN1HPGDKMT2ACETP | |
| SCHEMBL8218736 | 0.99 | SYK (0.45) | ALDH1A1MEN1HPGDKMT2ASYK | |
| SCHEMBL8218735 | 0.99 | SYK (0.45) | ALDH1A1MEN1HPGDKMT2ASYK | |
| SCHEMBL18634633 | 0.91 | CA2 (0.47) | ALDH1A1SYKCYP3A4TSHRMAPK1 | |
| SCHEMBL973865 | 0.91 | CA2 (0.47) | ALDH1A1SYKCYP3A4TSHRMAPK1 | |
| SCHEMBL7531812 | 0.90 | ALDH1A1 (0.46) | ALDH1A1MEN1HPGDKMT2ASYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0621270-B1 | Piperazine derivatives as collagenase inhibitors | SANKYO CO (JP) | 2000-04-12 | — | — | EP | disclosed |
| US-5643908-A | ANGIOGENESIS INHIBITOR, ANTITUMOR | SANKYO COMPANY, LIMITED (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0621270-A1 | COLLAGENASE INHIBITOR | SANKYO COMPANY LIMITED (JP) | 1994-10-26 | — | — | EP | disclosed |