Toluene

Toluene

SCHEMBL821885

Cc1ccccc1.NS(=O)(=O)O

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.58
LMNA P02545 1/20 0.58
ALOX12 P18054 1/20 0.58
ACHE P22303 1/20 0.58
CA1 P00915 9/20 0.48
CA2 P00918 9/20 0.48
CA9 Q16790 8/20 0.48
CA5A P35218 4/20 0.48
CA12 O43570 4/20 0.48
CA6 P23280 3/20 0.48
CA7 P43166 3/20 0.48
CA5B Q9Y2D0 3/20 0.48
CA3 P07451 2/20 0.48
CA4 P22748 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
PLA2G7 Q13093 1/20 0.46
CA13 Q8N1Q1 1/20 0.46
CA14 Q9ULX7 1/20 0.46
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL27594908 0.97 TSHR (0.55) TSHRLMNAALOX12ACHECA1
Toluene SCHEMBL21814538 0.95 TSHR (0.52) TSHRLMNAALOX12ACHECA1
Toluene SCHEMBL11123126 0.89 LMNA (0.65) TSHRLMNAALOX12ACHECA1
Toluene SCHEMBL664006 0.89 ALOX12 (0.65) TSHRLMNAALOX12ACHECA1
Toluene SCHEMBL248686 0.89 LMNA (0.65) TSHRLMNAALOX12ACHECA1
Toluene SCHEMBL10424511 0.87 LMNA (0.44) TSHRLMNAALOX12ACHECA1
Toluene SCHEMBL7627695 0.86 LMNA (0.61) TSHRLMNAALOX12ACHECA1
Toluene SCHEMBL5070324 0.86 LMNA (0.61) TSHRLMNAALOX12ACHECA1
Toluene SCHEMBL30489134 0.86 TSHR (0.61) TSHRLMNAALOX12ACHECA1
Toluene SCHEMBL6518753 0.86 LMNA (0.61) TSHRLMNAALOX12ACHECA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-54043956-A None JP disclosed
US-11807754-B2 Heat-curable urethane resin composition, film, and article DIC CORPORATION (JP) 2023-11-07 US disclosed
US-20210163738-A1 HEAT-CURABLE URETHANE RESIN COMPOSITION, FILM, AND ARTICLE DIC CORPORATION (JP) 2021-06-03 US disclosed
CN-104478360-B A kind of mine reinforcing material 北方工业大学 2017-01-04 CN disclosed
CN-104446274-B A kind of high-strength quick-solidifying material 北方工业大学 2016-08-24 CN disclosed
CN-104478278-B A kind of mine reinforcing additive 北方工业大学 2016-08-17 CN disclosed
EP-2098578-B1 MOISTURE-CURABLE POLYURETHANE HOT-MELT ADHESIVE, LAMINATES MADE WITH THE SAME, AND MOISTURE-PERMEABLE FILM DAINIPPON INK & CHEMICALS (JP) 2016-03-23 EP disclosed
US-8277930-B2 Moisture-permeable film, production method of same and laminate using same DIC CORPORATION (JP) 2012-10-02 US disclosed
US-20110287242-A1 MOISTURE-PERMEABLE FILM, PRODUCTION METHOD OF SAME AND LAMINATE USING SAME DIC CORPORATION (JP) 2011-11-24 US disclosed
US-7914896-B2 Moisture-curable polyurethane hot melt adhesive, and laminate and moisture-permeable film using the same DIC CORPORATION (JP) 2011-03-29 US disclosed
EP-0845816-A1 SOLAR CELL MODULE AND ITS MANUFACTURING METHOD SUNSTAR GIKEN KABUSHIKI KAISHA (JP) 1998-06-03 EP disclosed
US-5084593-A Cyanine, aniline dyes for heat sensitive recording elements RICOH COMPANY, LTD. (JP) 1992-01-28 US disclosed
EP-0280284-B1 HEAT-SENSITIVE RECORDING MATERIAL JUJO PAPER CO., LTD. (JP) 1991-09-18 EP disclosed
US-5008238-A Thermosensitive material with phenolic developer RICOH COMPANY, LTD. (JP) 1991-04-16 US disclosed
EP-0280284-A2 Heat-sensitive recording material JUJO PAPER CO., LTD. (JP) 1988-08-31 EP disclosed
US-4717710-A CHROMOGEN, TRIAZOLE, AZOMETHINE OR CARBOXYLIC ACID AMINE SALT, AND AN ALCOHOL, AMIDE OR ESTER SOLVENT MATSUI SHIKISO CHEMICAL CO. LTD. (JP) 1988-01-05 US disclosed
EP-0231030-A2 A thermochromic polyurethane foam and a method for producing the foam MATSUI SHIKISO CHEMICAL CO., LTD (JP) 1987-08-05 EP disclosed
EP-0188635-A1 Thermochromic composition MATSUI SHIKISO CHEMICAL CO., LTD (JP) 1986-07-30 EP disclosed
US-4515849-A Transfer printing sheet, printing method and printed article MATSUI SHIKISO CHEMICAL CO. LTD. (JP) 1985-05-07 US disclosed
JP-S5443956-A PREPARTION OF FLEXIBLE MELAMIME RESIN MATSUSHITA ELECTRIC WORKS LTD 1979-04-06 JP disclosed