Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17995472 | 0.74 | TSHR (0.43) | TSHRCYP2C9MAPK1LMNA | |
| SCHEMBL1474193 | 0.74 | TSHR (0.43) | TSHRCYP2C9MAPK1ALDH1A1LMNA | |
| SCHEMBL1474192 | 0.74 | TSHR (0.43) | TSHRCYP2C9MAPK1ALDH1A1LMNA | |
| SCHEMBL14278564 | 0.68 | TSHR (0.37) | TSHRCYP2C9MAPK1LMNA | |
| SCHEMBL12203799 | 0.67 | MAPK1 (0.49) | TSHRCYP2C9MAPK1ALDH1A1LMNA | |
| SCHEMBL821246 | 0.67 | ATM (0.35) | — | |
| SCHEMBL11364805 | 0.66 | — | — | |
| SCHEMBL29574771 | 0.66 | KMT2A (0.38) | — | |
| SCHEMBL7649225 | 0.65 | CA1 (0.41) | ALDH1A1LMNA | |
| SCHEMBL663720 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2390276-B1 | CARBOXYL GROUP-CONTAINING POLYURETHANE | SHOWA DENKO KK (JP) | 2018-06-13 | — | — | EP | disclosed |
| US-8674017-B2 | (Poly)carbonate polyol and carboxyl group-containing polyurethane obtained from the (poly)carbonate polyol | SHOWA DENKO K.K. (JP) | 2014-03-18 | — | — | US | disclosed |
| EP-2390276-A1 | CARBOXYL GROUP-CONTAINING POLYURETHANE | Showa Denko K.K. (JP) | 2011-11-30 | — | — | EP | disclosed |
| EP-2390277-A1 | (POLY)CARBONATE POLYOL AND CARBOXYL GROUP-CONTAINING POLYURETHANE USING THE (POLY)CARBONATE POLYOL AS STARTING MATERIAL | Showa Denko K.K. (JP) | 2011-11-30 | — | — | EP | disclosed |
| US-20110272182-A1 | CARBOXYL GROUP-CONTAINING POLYURETHANE | SHOWA DENKO K.K. (JP) | 2011-11-10 | — | — | US | disclosed |
| US-20110272183-A1 | (POLY)CARBONATE POLYOL AND CARBOXYL GROUP-CONTAINING POLYURETHANE OBTAINED FROM THE (POLY)CARBONATE POLYOL | SHOWA DENKO K.K. (JP) | 2011-11-10 | — | — | US | disclosed |
| US-20110257257-A1 | COMPOSITION FOR TREATMENT OF EPITHELIAL TISSUE | NOVODERMIX INTERNATIONAL LIMITED (VG) | 2011-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110272183-A1 | (POLY)CARBONATE POLYOL AND CARBOXYL GROUP-CONTAINING POLYURETHANE OBTAINED FROM THE (POLY)CARBONATE POLYOL | PUF60, PARG, PIK3C2G | TSHR 4843/4885CYP2C9 1807/4885MAPK1 3436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.