SCHEMBL17995472

SCHEMBL17995472

CC1CCCCC12CCCC(=O)O2

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.43
LMNA P02545 1/20 0.43
MAPK1 P28482 2/20 0.36
CYP2C9 P11712 1/20 0.36
SIRT2 Q8IXJ6 1/20 0.33
MAPT P10636 1/20 0.33
CA1 P00915 2/20 0.32
CA2 P00918 1/20 0.32
CA4 P22748 1/20 0.32
CA9 Q16790 1/20 0.32
KMT2A Q03164 1/20 0.31
CYP2D6 P10635 1/20 0.31
AKR1C3 P42330 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1474193 0.93 TSHR (0.43) TSHRLMNAMAPK1CYP2C9MAPT
SCHEMBL1474192 0.93 TSHR (0.43) TSHRLMNAMAPK1CYP2C9MAPT
SCHEMBL14278564 0.87 TSHR (0.37) TSHRLMNAMAPK1CYP2C9MAPT
SCHEMBL12203799 0.75 MAPK1 (0.49) TSHRLMNAMAPK1CYP2C9MAPT
SCHEMBL821890 0.74 TSHR (0.31) TSHRLMNAMAPK1CYP2C9
SCHEMBL17995484 0.70 TSHR (0.47) TSHRLMNAMAPK1CYP2C9MAPT
SCHEMBL16797125 0.70 TSHR (0.40) TSHRLMNAMAPK1CYP2C9MAPT
SCHEMBL31695364 0.67 LMNA (0.37) TSHRLMNA
SCHEMBL17262936 0.66 KMT2A (0.35) TSHRLMNACA1CA2CA4
SCHEMBL2997663 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016125782-A1 NOVEL ALICYCLIC ESTER COMPOUND, (METH)ACRYLIC COPOLYMER, AND FUNCTIONAL RESIN COMPOSITION CONTAINING SAME 三菱瓦斯化学株式会社 2016-08-11 WO disclosed